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Toxicological Aspects of Medical Device Implants

Author: Prakash Srinivasan Timiri Shanmugam

Publisher: Academic Press

Published: 2020-06-10

Total Pages: 331

ISBN-13: 0128209208

Toxicological Aspects of Medical Device Implants provides comprehensive information on the use of medical implant and devices and the balance between the application of the devices in relation to any potential adverse effects. In order to ensure the safety and effectiveness of medical devices, many international policies, regulations, and standards have been established, and the book also discusses medical devices within this regulatory framework. The book covers a broad range of disease topics and disease-specific implants and an interdisciplinary team of experts brings a wealth of information on implants used in various disease models and associated risk factors. Toxicological Aspects of Medical Device Implants is a comprehensive resource for toxicologists, biomedical engineers, immunologists, medical staff, regulators, and manufacturers working in the field who need to be aware of the potential toxicity and device management of such a wide variety of implants and devices and their health risks. Discusses the adverse toxicological effects of medical devices Covers a broad range of disease topics and disease specific implants Offers contributions from experts from across several disciplines

Biomedical Implants

Author: Ravi K. Dwivedi

Publisher: CRC Press

Published: 2024-02-14

Total Pages: 265

ISBN-13: 1003851096

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This book provides a comprehensive overview of the development of implants, from the selection of materials to the outcome of the process. It covers various steps, including biocompatible material, synthesis, and characterization, compatibility and limitations of materials, specific implants, and finite element analysis of medical implants. It also presents a comparison between predictions and experimental results by studying real-world problems and addresses the issue of sustainability in implant manufacturing, process modeling, and optimization in additive manufacturing supported by case studies. Features: • Covers the development of implants from the selection of material to the suitable process of manufacturing technologies. • Includes biocompatible material, synthesis, characterization, compatibility, and limitations of materials. • Reviews biofabrication in terms of artificial organs and soft tissues. • Discusses implant manufacturing, including additive and micro-manufacturing and failure analysis through case studies. • Addresses the issue of sustainability in implant manufacturing. This book is intended for researchers and graduate students specializing in mechanical, biomedical, healthcare engineering, biomaterials, and additive manufacturing.

Biotextiles as Medical Implants

Author: M W King

Publisher: Elsevier

Published: 2013-10-31

Total Pages: 739

ISBN-13: 0857095609

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Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable polymers and shaped biotextiles. The chapters in part two provide a comprehensive discussion of a range of different clinical applications of biotextiles, including surgical sutures, arterial prostheses, stent grafts, percutaneous heart valves and drug delivery systems.This book provides a concise review of the technologies, properties and types of biotextiles used as medical devices. In addition, it addresses the biological dimension of how to design devices for different clinical applications, providing an invaluable reference for biomedical engineers of medical textiles, quality control and risk assessment specialists, as well as managers of regulatory affairs. The subject matter will also be of interest to professionals within the healthcare system including surgeons, nurses, therapists, sourcing and purchasing agents, researchers and students in different disciplines. Provides an invaluable single source of information on the main types of textile materials and products used for medical implants Addresses the technologies used and discusses the manufacture, properties and types of biotextiles Examines applications of biotextiles as medical implants, including drug delivery systems and stent grafts and percutaneous heart valves

Surface Engineering and Technology for Biomedical Implants

Author: Yoshiki Oshida

Publisher: Momentum Press

Published: 2014-04-15

Total Pages: 251

ISBN-13: 1606506285

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This new book synthesizes a wide range of interdisciplinary literature to provide the state-of-the art of biomedical implants. It discusses materials and explains the three basic requirements for implant success from a surface engineering perspective: biological compatibility, biomechanical compatibility, morphological compatibility. Biomedical, mechanical, and materials engineers will find this book indispensable for understanding proper treatment of implant surfaces in order to achieve clinical success. Highlights include: • Coverage of surface engineering of polymer, metallic, ceramic and composite implant materials; • Coverage of chemical, mechanical, physical, thermal, and combined surface modification technologies; • Explanations of interfacial reaction between vital tissue and non-vital implant surface; and • Methodologies and technologies for modification of surface layer/zone to promote the osteo-integration, the ultimate success for biomedical implants in both dental and medical practice.

Proceedings of the Symposium on Compatability of Biomedical Implants

Author: Paul Kovacs

Publisher: The Electrochemical Society

Published: 1994

Total Pages: 430

ISBN-13: 9781566770477

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Biomedical Implants

Author: Ravi K. Dwivedi

Publisher:

Published: 2024

Total Pages: 0

ISBN-13: 9781003375098

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This book provides a comprehensive overview of the development of implants, from the selection of materials to the outcome of the process. It covers various steps, including biocompatible material, synthesis, and characterization, compatibility and limitations of materials, specific implants, and finite element analysis of medical implants. It also presents a comparison between predictions and experimental results by studying real-world problems and addresses the issue of sustainability in implant manufacturing, process modeling, and optimization in additive manufacturing supported by case studies. Features: Covers the development of implants from the selection of material to the suitable process of manufacturing technologies Includes biocompatible material, synthesis, characterization, compatibility, and limitations of materials Reviews biofabrication in terms of artificial organs and soft tissues Discusses implant manufacturing, including additive and micro-manufacturing and failure analysis through case studies Addresses the issue of sustainability in implant manufacturing This book is intended for researchers and graduate students specializing in mechanical, biomedical, healthcare engineering, biomaterials, and additive manufacturing.

Polymer-Based Additive Manufacturing

Author: Declan M. Devine

Publisher: Springer Nature

Published: 2019-09-16

Total Pages: 277

ISBN-13: 3030245322

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This book aims to give readers a basic understanding of commonly used additive manufacturing techniques as well as the tools to fully utilise the strengths of additive manufacturing through the modelling and design phase all the way through to post processing. Guidelines for 3D-printed biomedical implants are also provided. Current biomedical applications of 3D printing are discussed, including indirect applications in the rapid manufacture of prototype tooling and direct applications in the orthopaedics, cardiovascular, drug delivery, ear-nose-throat, and tissue engineering fields. Polymer-Based Additive Manufacturing: Biomedical Applications is an ideal resource for students, researchers, and those working in industry seeking to better understand the medical applications of additive manufacturing.

Biointegration of Medical Implant Materials

Author: Chandra P. Sharma

Publisher: Elsevier

Published: 2010-07-13

Total Pages: 429

ISBN-13: 1845699807

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Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue. Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering. With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration Discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction Reviews particular techniques in drug delivery featuring inorganic nanoparticles and functionalized nanoparticles for targeted drug delivery

Service Characteristics of Biomedical Materials and Implants

Author: Andrew W. Batchelor

Publisher: Imperial College Press

Published: 2004

Total Pages: 260

ISBN-13: 1860945368

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A wide variety of materials is being used in biomedical engineering for various functions. This includes a range of ceramics, polymers and metallic materials for implants and medical devices. A major question is how these materials will perform inside the body, which is very sensitive to alien materials.

Polymeric Materials for Biomedical Implants

Author: Sabu Thomas

Publisher: Elsevier

Published: 2023-10-17

Total Pages: 642

ISBN-13: 0323996914

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Polymeric Materials for Biomedical Implants: Characterization, Properties, and Applications offers a comprehensive guide to the various polymers utilized in the development and application of biomedical implants. These materials possess unique properties which make them ideal for use in biomedical implants, including their high degree of flexibility, ease of fabrication, non-magnetic and radio transparent properties for medical imaging, and ease of engineering for biocompatibility. The book thoroughly reviews the properties, characterization and a broad range of applications of polymeric materials in biomedical implants, bringing all key information on this important topic together under a single reference. The book's chapters cover vital topics for the development of polymeric biomedical implants, including biomaterial-tissue interactions, mechanical and surface property requirements for different implants, as well as market and ethical issues. This will be a useful reference for academics and researchers working in materials science, biomedical engineering, regenerative medicine and pharmacology, as well as R&D groups developing biomedical implants. Helps the reader make an informed choice when selecting polymeric materials for use in biomedical implants Covers a broad range of applications of biomedical implants, including cancer therapy, orthopedics, cardiovascular, biosensing and wound healing Emphasizes the importance of biocompatibility, with chapters covering toxicity and degradation aspects, as well as biomaterial-tissue interactions and the foreign body response