Biology of Cardiovascular and Metabolic Diseases

Biology of Cardiovascular and Metabolic Diseases PDF

Author: Chaya Gopalan

Publisher: Academic Press

Published: 2022-01-11

Total Pages: 268

ISBN-13: 0128234229

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Biology of Cardiovascular and Metabolic Diseases combines physiology and pathophysiology of selected metabolic and cardiovascular diseases with health relevance. Written in a concise and easy to read manner, the book allows readers to gain an understanding on a number of topics, including cardiovascular physiology and pathophysiology and how it relates to the development of insulin resistance, diabetes and other metabolic diseases. The book also highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure and way to treat underlying conditions. Focuses succinctly on the physiology and pathophysiology of cardiovascular and metabolic diseases Written in a concise and easy to read manner, allowing readers to quickly understand concepts Highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure

Cardiovascular and Metabolic Disease

Cardiovascular and Metabolic Disease PDF

Author: Philip Peplow

Publisher: Royal Society of Chemistry

Published: 2015-05-22

Total Pages: 396

ISBN-13: 178262046X

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Cardiovascular and metabolic diseases remain the number one cause of death in developed countries and their prevalence is increasing rapidly in developing nations. This book brings together the recent information on these disorders and the links that exist between them in order to provide a complete picture of drug discovery for these conditions. The main three sections comprehensively discuss obesity, hypertension and cardiovascular disease, and diabetes in turn, following an introduction to the molecular links between them. The final chapter provides perspectives on future directions of the field. Chapters are contributed by leaders in the field from academia and industry and cover biomarkers, risk factors, gene-environment interactions, therapies and the various types of animal models that have been used to study each disease. Case studies describing the implementation of animal models in drug development further enhance the book’s usefulness as a comprehensive guide to this important therapeutic area. Providing a full picture of the various types of animal models that have been used to study obesity, hypertension, and insulin resistance with recent case studies, this book provides a valuable resource for medicinal chemists and clinicians working in these disease areas.

Prevention and Management of Cardiovascular and Metabolic Disease

Prevention and Management of Cardiovascular and Metabolic Disease PDF

Author: Peter Kokkinos

Publisher: John Wiley & Sons

Published: 2023-04-24

Total Pages: 421

ISBN-13: 1119833442

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Prevention and Management of Cardiovascular and Metabolic Disease Provides accurate and well-documented information on the impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases and healthy aging. This authoritative textbook examines the independent and combined impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases, with special emphasis on the elderly populations. In this book the authors: Provide the latest data on the association between a suboptimal diet and physical inactivity and chronic disease. Examine the role of epigenetics on longevity. Discuss the fundamentals of healthy aging. Highlight the role of well-known dietary patterns such as the Mediterranean diet and the Nordic diet in favorable health outcomes, including cardiovascular, metabolic health, and healthy aging. Discuss the health outcomes of physical activity and healthy aging. Present the most recent evidence-based data on the independent and synergistic impact of diet and exercise on disease prevention and management including, heart disease, diabetes mellitus, hypertension, dyslipidemia, kidney failure, cancer and other conditions. Prevention and Management of Cardiovascular and Metabolic Disease: Diet, Physical Activity and Healthy Aging is an excellent textbook for upper-level undergraduate and graduate students in medical and health-related disciplines and for health professionals, including dietitians and nutritionists, exercise physiologists, athletic trainers, nurses, physicians, geriatricians, and other health professionals with a special focus in older adults. This book is also a highly useful reference for health professionals interested in introducing diet and physical activity as an intervention for healthy aging as well as the prevention and management of cardiovascular and other metabolic diseases that are prevalent in aging populations.

Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease

Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease PDF

Author: Thomas Pulinilkunnil

Publisher: Frontiers Media SA

Published: 2019-08-08

Total Pages: 89

ISBN-13: 2889459381

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Metabolic Disorders and Shen in Integrative Cardiovascular Chinese Medicine

Metabolic Disorders and Shen in Integrative Cardiovascular Chinese Medicine PDF

Author: Anika Niambi Al-Shura

Publisher: Academic Press

Published: 2020-07-30

Total Pages: 108

ISBN-13: 0128189231

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Metabolic Disorders and Shen in Integrative Cardiovascular Medicine, volume seven in the Integrative Cardiovascular Chinese Medicine series, presents the connection between metabolic diseases that affect the cardiovascular system and mental health through both Chinese and Western medicine explanations. Sections discuss the etiology of metabolic disorders of blood sugar disorders, lipid disorders, inflammatory disorders and shen, the clinical significance and differentiations in both Western and Chinese medicine, and prescriptions and the medicated diet, including main acupoints, remedies and medicines used in Western and Chinese medicine and the combination of medicinal herbs and food for Chinese diet therapy. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base that not only guides clinical practice, but also encourages collaboration between Chinese and Western medicine practitioners. Gives basic medical science and TCM theory background on lipids, blood sugar, inflammation and shen with clinical significance and diagnosis Provides treatment methods and advice, including nutritional therapy and the Chinese medicine dietary plan Prepares readers for advanced study within Integrative Cardiovascular Chinese Medicine

Cardiac Energy Metabolism in Health and Disease

Cardiac Energy Metabolism in Health and Disease PDF

Author: Gary D. Lopaschuk

Publisher: Springer

Published: 2014-08-22

Total Pages: 301

ISBN-13: 1493912275

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The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

Extracellular Vesicles in Cardiovascular and Metabolic Diseases

Extracellular Vesicles in Cardiovascular and Metabolic Diseases PDF

Author: Junjie Xiao

Publisher: Springer Nature

Published: 2023-09-22

Total Pages: 272

ISBN-13: 9819914434

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This book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.

Oxidative Stress in Cardiovascular-Metabolic Diseases

Oxidative Stress in Cardiovascular-Metabolic Diseases PDF

Author: Ali Hussein Eid

Publisher: Springer

Published: 2024-09-19

Total Pages: 0

ISBN-13: 9783031621307

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The book dissects the role of oxidative stress in the pathogenesis of the leading causes of global morbidity and mortality, i.e.cardiovascular and metabolic diseases. The chapters discuss topics related to the role reactive oxygen species (ROS) play in hypertension, atherosclerosis,diabetes, obesity and related pathologies. The authors also shed light on gender differences in the onset and pathologies of some of these diseases. Moreover, how ROS and aging interplay to precipitate cardiovasculo-metabolic disease is discussed and highlighted. Preventive measures that can abrogate ROS-induced cardiovasclo-metabolic disease are discussed and clarified in the hope of reducing such a debilitating battery of diseases. A section dedicated to antioxidants as potential therapy is also included. Furthermore, given the complexity of the mechanisms implicated in ROS-modulated responses, it remains challenging to assert a conclusive argument and pre-determined regimen for incorporating antioxidants into conventional therapies. Nonetheless, results from some clinical trials appear promising, warranting the addition of a chapter dedicated to such human trials. In all of the chapters, the molecular, cellular, genetic, and pharmacological mechanisms implicated are covered from an applied science perspective. This is an ideal book for basic researchers in the biomedical field, graduate students in biological and biomedical fields, medical students, instructors in medical and graduate schools, and professionals working for pharmaceutical companies.

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