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Textbook of Biological Psychiatry

Author: Jaak Panksepp

Publisher: John Wiley & Sons

Published: 2004-02-15

Total Pages: 736

ISBN-13: 0471468983

A Textbook of Biological Psychiatry integrates the basic science concerning brain mechanisms of psychiatric disorders alongside surveys of present standard clinical treatment. Organized in a coherent and easy to follow structure, chapters expand across different levels of analysis, from basic mechanisms to clinical practice. This comprehensive reference provides an integrative treatment of the biochemistry of neurotransmission, behavioral pharmacology, and clinical aspects of psychiatric problems including depression, manic-depression, and mood disorders. Other chapters address the biological mechanisms and treatment of depression, anxiety, panic, obsessive-compulsive disorder, and addictions. The editor concludes with a perspective on the future of the field and prospects for understanding and effectively treating mood and anxiety disorders.

Biological Psychiatry

Author: Michael R. Trimble

Publisher: John Wiley & Sons

Published: 2010-12-07

Total Pages: 440

ISBN-13: 0470975881

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Biological psychiatry has dominated psychiatric thinking for the past 40 years, but the knowledge base of the discipline has increased substantially more recently, particularly with advances in genetics and neuroimaging. The third edition of Biological Psychiatry has been thoroughly updated taking into account these developments. As in the earlier editions of the book, there are comprehensive reviews and explanations of the latest advances in neurochemistry, neuroanatomy, genetics and brain imaging— descriptions not only of methodologies but also of the application of these in clinical settings. It is within this context that there is a considerable emphasis in the book on brain–behaviour relationships both within and without the clinical setting. This edition has been enhanced by the inclusion of new chapters, one on anxiety and another on motivation and the addictions. The chapter that relates to treatments has been extended to include the latest information on brain stimulation techniques. The overall book is well illustrated in order to help with an understanding of the text. For the third edition, Professor Michael Trimble has been joined by Professor Mark George as co-author. These are two of the world's leading biological psychiatrists who both have considerable clinical as well as research experience which they have brought to the book. Unlike multiauthored texts, it has a continuity running through it which aids understanding and prevents repetition. This book is strongly recommended for all practising psychiatrists and trainees wishing for an up-to-date, authoritative, easy to digest and acessible review of the latest advances and conceptualizations in the field. It will also appeal to neurologists interested in neuropsychiatry and biological psychiatry or the psychiatric aspects of neurological disorders, as well as other practising clinicians (psychologists, social workers, nurses) in the mental health field.

African Origin of Biological Psychiatry

Author: Dr Richard D King

Publisher:

Published: 2012-03-01

Total Pages: 150

ISBN-13: 9780984887309

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How to Become a Schizophrenic

Author: John Modrow

Publisher: iUniverse

Published: 2003-02-25

Total Pages: 436

ISBN-13: 1469793725

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demonstrates the physical, psychological, and social harm resulting from the label schizophrenic and the continuous need to reexamine the underpinnings and attitudes of psychiatry. Booklist Of all the books written about schizophrenianone is more comprehensive, accurate, thorough, and clearer in style and statement than John Modrows classic How to Become a Schizophrenic. Modrow, who is a recovered schizophrenic and is, perhaps, the unrecognized and unappreciated worlds foremost authority on this disorder, has performed a truly invaluable service and has made the major contribution to our understanding of the causes and cures of this pseudodisease. Robert A Baker, Ph.D., former chairman of the Department of Psychology, University of Kentucky; author of They Call It Hypnosis, Hidden Memories: Voices and Visions from Within and Mind Games: Are We Obsessed with Therapy? One of the best things Ive read on the subjectI am struck by the richness of the ideas and the research and the soundness of the conclusions. Peter Breggin, M.D., founder and director of the International Center for the Study of Psychiatry and Psychology; author of Toxic Psychiatry and Talking Back to Prozac a very important contribution to the field. Theodore Lidz, M.D., former chairman of the Department of Psychiatry, Yale University; author of The Origin and Treatment of Schizophrenic Disorders and Schizophrenia and the Family well researched and easily readable (a difficult combination to achieve)! Judi Chamberlin, author of On Our Own: Patient-Controlled Alternatives to the Mental Health System meticulously challenges all the major research that claims that schizophrenia is a biological disorder. Ty C. Colbert, Ph.D., author of Broken Brains or Wounded Hearts: What Causes Mental Illness Before reading the book, I was largely convinced that schizophrenia was primarily a brain disease. Modrow has forced me to take a second look, however, and reconsider the psychological causes of the condition. The Vancouver Sun it is ennobling that despite bad and discouraging treatment he was able to understand himself and others, and share that acquired knowledge in an accurate and helpful way. Bertram P. Karon, PhD., professor of clinical psychology, Michigan State University; author of Psychotherapy of Schizophrenia gives clear proof that theres real hope. Truly a remarkable book! Alan Caruba, Bookviews

Understanding Biological Psychiatry

Author: Robert J. Hedaya

Publisher: W. W. Norton

Published: 1996

Total Pages: 311

ISBN-13: 9780393701913

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Beginning with a tour of the brain, Dr. Hedaya explains how the brain works and how brain function relates to physical symptoms and cognitive and emotional well-being. He explains how biological psychiatrists consider the biology of the individual as an integral part of the whole picture and demonstrates a new way of conceptualizing clinical problems. Understanding Biological Psychiatry provides information in three basic areas: Chapters 1 and 2 outline basic scientific foundations and core concepts in biological psychiatry; chapters 3 and 4 review biological theories and medical mimics of the major psychiatric disorders; chapters 5 and 6 discuss medication and practical issues, including the basics of psychotropic medications and their role in the biopsychosocial approach. At the heart of this book is the author's proposal for a working alliance between therapists and psychiatrists - an important goal in today's growing managed care environment. The book has a practical bent, discussing, for example, when and how to refer to a psychiatrist, even describing how to explain this new perspective to a patient. The author's conversational style, as well as many figures, tables, and case illustrations, makes Understanding Biological Psychiatry a guide that is sure to be well-read and often referred to by therapists and physicians, as well as psychiatrists wanting to brush up on the biology of the mind.

Biological Psychiatry

Author: Edward Bittar

Publisher: Elsevier

Published: 1999-12-27

Total Pages: 641

ISBN-13: 9780080528007

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It is now widely recognised that biological psychiatry is rapidly coming into its own. For over the last three decades dramatic advances in this young discipline have been made, all of which attest to the staying power of the experimental method. Those who made this revolution in knowledge happen are a breed of investigators availing themselves of the tools of molecular biology, pharmacology, genetics, and perhaps, above all, the technology of neuroimaging. The introduction of the interdisciplinary method of approach to the study of psychopathology had made it very clear that neuroimaging, as a set of techniques, is unique in that it is gradually providing us with evidence supporting Kraepelin's original view that mental illness is closely associated with abnormal changes in the brain. Broadly speaking, there are presently two structural techniques in neuroimaging - computed tomography and magnetic resonance imaging (MRI) - and three functional techniques - single photon emission tomography (SPECT), positron emission tomography and magnetic resonance imaging (fMRI). Through PET technology, for example, we have learned that, in early brain development, the primitive areas, mostly the brain stem and thalamus, are the first to show high activity in an infant. This is followed by the development of cortical areas by year one. Between the ages of four to 10, the cortex is almost twice as active in the child as in the adult. This information alerts us to what might happen in the way of trauma in abused children, especially those under the age of three. Child abuse increases the risk of physical changes, not only in the stress systems, but also in brain development (Glaser and Weissman). In addition to the difficult problem of post-traumatic stress disorder (PTSD), we have to take into account the possibility of other types of mental illness as the consequences of child abuse. These include depression, eating disorders, and drug and alcohol problems. The combination of PET and fMRI represents a more remarkable example of the power of neuroimaging since the two have made it feasible to map accurately in vitro identifiable cortical fields, or networks. In a landmark NIH investigation of human cortical reorganization (plasticity), persuasive evidence was brought forward showing that the process of learning as a motor task involves a specific network of neurons. These neurons occur in the cortical field that is responsible for that particular task. Such findings are important partly because they provide evidence supporting the current notion that labor in the cortex is divided among ensembles of specialized neurons that cooperate in the performance of complex tasks. Cooperation, then, in this, sense implies crosstalk among ensembles and that signals are both processed and retransmitted to neighbouring ensembles. To understand the workings of these ensembles, much better spatial and temporal resolution in functional brain mapping is required. This can be achieved with an NMR instrument whose magnet is 4.1 Tesla or more.

Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness

Author: Anne Harrington

Publisher: W. W. Norton & Company

Published: 2019-04-16

Total Pages: 384

ISBN-13: 1324001976

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Mind Fixers tells the history of psychiatry’s quest to understand the biological basis of mental illness and asks where we need to go from here. In Mind Fixers, Anne Harrington, author of The Cure Within, explores psychiatry’s repeatedly frustrated struggle to understand mental disorder in biomedical terms. She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds. But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time. Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well. In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones. A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.

Personalized Psychiatry

Author: Bernhard Baune

Publisher: Academic Press

Published: 2019-10-16

Total Pages: 604

ISBN-13: 0128131772

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Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Frontiers in Psychiatry

Author: Yong-Ku Kim

Publisher: Springer Nature

Published: 2019-11-09

Total Pages: 641

ISBN-13: 9813297212

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This book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.

Pseudoscience in Biological Psychiatry

Author: Colin A. Ross

Publisher: John Wiley & Sons

Published: 1995

Total Pages: 312

ISBN-13:

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Lately, it seems that not a day passes without the media proclaiming yet another sensational breakthrough in the search for the physical origins of mental illness. But beyond all the fanfare and media hype, is there a single shred of hard, empirical evidence to substantiate the existence of "a gene for alcoholism," or "the brain chemistry behind schizophrenia"? More to the point, in fact, is it scientifically sound to limit the search for the roots of mental illness to processes occurring within the body, while dismissing socioeconomic, familial, and experiential influences as, at best, mere "triggering mechanisms"? And, if not, what harm is being done by psychiatry's current obsession with these somatic chimeras? This groundbreaking book offers answers to those questions and more. While Dr. Ross and Professor Pam clearly assert from the outset that biological psychiatry "is dominated by a reductionist ideology which distorts and misrepresents much of its research," this is by no means a raw polemic voiced by an overzealous opposition. Instead, it is a reasoned discourse based on a clear-sighted and methodical examination of the professional literature. Contributors to this volume include distinguished researchers and clinicians from the fields of psychiatry, psychology, sociology, and psychopharmacology. Their common purpose in coming together was to alert the mental health community to the ideological blind spots and conceptual errors in the basic logic and methodology of biological psychiatry, to demonstrate the need for a more scientifically based psychiatric practice, and to suggest alternative approaches to understanding and treating mental illness. Readers will find their arguments stimulating, provocative, and highly persuasive. Among the cutting-edge issues they explore are: the historical origins of biological psychiatry; genetics and mental illness; the current state of psychiatric training; psychopharmacology and drug therapy; the public health, legal, and ethical implications of biological psychiatry; and the funding, power, and politics of research. This book is essential reading for all mental health professionals. It also has many important things to say to health care administrators, political analysts, and public policy-makers. Of related interest . . . INSANITY The Idea and Its Consequences Thomas Szasz In this provocative book, Dr. Thomas Szasz, one of the most celebrated and controversial psychiatric thinkers of our time, presents a carefully crafted, systematic analysis of the precise character and practical consequences of the idea of mental illness. His findings and opinions have captured the attention of organized psychiatry and given everyone concerned with the human condition a better understanding of this almost universally misunderstood "disease." 1990 (0-471-52534-0) 432 pp. CRUEL COMPASSION Psychiatric Control of Society's Unwanted Thomas Szasz Cruel Compassion is the capstone of Thomas Szasz's critique of psychiatric practices. Reexamining psychiatric interventions from a cultural-historical and political-economic perspective, Szasz demonstrates that the main problem that faces mental health policymakers today is adult dependency. He gives us a sobering look at some of our most cherished notions about our humane treatment of society's unwanted and about ourselves as a compassionate and democratic people. 1994 (0-471-01012-X) 260 pp.