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Biologic Markers in Pulmonary Toxicology

Author: National Research Council

Publisher: National Academies Press

Published: 1989-02-01

Total Pages: 198

ISBN-13: 9780309039925

Biologic markersâ€"indicators of biological exposure or changeâ€"offer the promise of early detection of disease caused by environmental exposure. Researchers have used these markers to discover indications of pulmonary damage from low-level ozone, a finding with serious implications for health professionals and environmental regulators. Biologic Markers in Pulmonary Toxicology is a comprehensive study of this use of biologic markers. Focusing on the respiratory tract as an entryway for airborne pollutants, this volume reviews new ways of measuring markers, the need for markers to indicate dose or exposure levels, noninvasive respiratory function tests for use with healthy humans to detect sensitivity to inhaled pollutants, approaches to evaluating markers down to the cellular and biochemical levels, and more.

Biologic Markers in Urinary Toxicology

Author: National Research Council

Publisher: National Academies Press

Published: 1995-08-28

Total Pages: 322

ISBN-13: 0309052289

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Diseases of the kidney, bladder, and prostate exact an enormous human and economic toll on the population of the United States. This book examines prevention of these diseases through the development of reliable markers of susceptibility, exposure, and effect and the promise that new technologies in molecular biology and sophisticated understanding of metabolic pathways, along with classical approaches to the study of nephrotoxicants and carcinogens, can be developed and prevention of the diseases achieved. The specific recommendations included in this book complement those made in the previous three volumes on biomarkers, Biologic Markers in Reproductive Toxicology (1989), Biologic Markers in Pulmonary Toxicology (1989), and Biologic Markers in Immunotoxicology (1991).

Biologic Markers in Immunotoxicology

Author: National Research Council

Publisher: National Academies Press

Published: 1992-02-01

Total Pages: 225

ISBN-13: 0309043891

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Are environmental pollutants threatening the human immune system? Researchers are rapidly approaching definitive answers to this question, with the aid of biologic markersâ€"sophisticated assessment tools that could revolutionize detection and prevention of certain diseases. This volume, third in a series on biologic markers, focuses on the human immune system and its response to environmental toxicants. The authoring committee provides direction for continuing development of biologic markers, with strategies for applying markers to immunotoxicology in humans and recommended outlines for clinical and field studies. This comprehensive, up-to-date volume will be invaluable to specialists in toxicology and immunology and to biologists and investigators involved in the development of biologic markers.

Biomarkers in Toxicology

Author: Ramesh C. Gupta

Publisher: Academic Press

Published: 2014-01-25

Total Pages: 1152

ISBN-13: 0124046495

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Biomarkers in Toxicology is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This book includes both vertebrate and non-vertebrate species models for toxicological testing and development of biomarkers. Divided into several key sections, this reference volume contains chapters devoted to topics in molecular-cellular toxicology, as well as a look at the latest cutting-edge technologies used to detect biomarkers of exposure and effects. Each chapter also contains several references to the current literature and important resources for further reading. Given this comprehensive treatment, Biomarkers in Toxicology is an essential reference for all those interested in biomarkers across several scientific and biomedical fields. Written by international experts who have evaluated the expansive literature to provide you with one resource covering all aspects of toxicology biomarkers Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure and effect of chemicals of different classes Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation and much more

Biologic Markers in Pulmonary Toxicology

Author: National Research Council

Publisher: National Academies Press

Published: 1989-02-01

Total Pages: 204

ISBN-13: 9780309039901

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Multiple Chemical Sensitivities

Author: Commission on Life Sciences

Publisher:

Published: 1992

Total Pages: 110

ISBN-13:

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Annotation Clinicians, researchers, and others discuss multiple chemical sensitivities, a controversial diagnostic label for a phenomenon related to exposure to chemical agents sustained both in indoor and outdoor environments. No index. An addendum to the preceding entry. Annotation c. by Book News, Inc., Portland, Or.

Biologic Markers in Urinary Toxicology

Author: Subcommittee on Biologic Markers in Urinary Toxicology

Publisher: National Academies Press

Published: 1995-08-11

Total Pages: 322

ISBN-13: 0309587794

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How Tobacco Smoke Causes Disease

Author:

Publisher:

Published: 2010

Total Pages: 728

ISBN-13:

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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.