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Bioengineering Innovative Solutions for Cancer

Author: Sylvain Ladame

Publisher: Academic Press

Published: 2019-11-27

Total Pages: 396

ISBN-13: 0128138874

Bioengineering Innovative Solutions for Cancer bridges the gap between bioengineering and cancer biology. It focuses on a ‘bottom up’ understanding of the links between molecules, cells, tissues, organs, organisms, and health and functions—all within a bioengineering context. Chapters cover the main methods, technologies and devices that could help diagnose cancer sooner (e.g., ultrasensitive imaging and sensing technologies) and helpful treatments (e.g., new, more targeted therapies). The book takes an interdisciplinary approach that is ideal for those who need the latest information on design techniques and devices that help treat cancer using new, more targeted therapies. By covering the many different ways engineers can deliver innovative solutions to tackle cancer, this book is a valuable read for researchers who have an ambition to make an impact on people’s life in either an academic or industrial setting. Connects bioengineering and cancer biology, providing information on sensors, imaging, therapies and in-vitro models Presents the most comprehensive coverage in the field of cancer engineering to date Provides an academic introduction to (molecular) bioengineering for students, regardless of scientific background (math's, physics, chemistry, biology) Highlights the unmet medical needs for bioengineers and the main technological breakthroughs to cancer biologists

Targeted Cancer Therapy in Biomedical Engineering

Author: Rishabha Malviya

Publisher: Springer Nature

Published: 2023-04-11

Total Pages: 949

ISBN-13: 9811997861

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This book highlights the role of Biomedical Engineering (BME) used in diagnosis (e.g., body scanners) and treatment (radiation therapy and minimal access surgery in order to prevent various diseases). In recent years, an important progress has been made in the expansion of biomedical microdevices which has a major role in diagnosis and therapy of cancer. When fighting cancer, efficacy and speed are of the utmost importance. A recently developed microfluidic chip has enabled a breakthrough in testing the efficacy of specialized cancer drugs. Effective cancer-targeting therapies will require both passive and active targeting strategies and a thorough understanding of physiologic barriers to targeted drug delivery. Targeted cancer treatments in development and the new combinatorial approaches show promise for improving targeted anticancer drug delivery and improving treatment outcomes. This book discusses the advancements and innovations in the field of BME that improve the diagnosis and treatment of cancer. This book is focused on bioengineering approaches to improve targeted delivery for cancer therapeutics, which include particles, targeting moieties, and stimuli-responsive drug release mechanisms. This book is a useful resource for students, researchers, and professionals in BME and medicine.

Emerging Cancer Therapy

Author: Arsenio Fialho

Publisher: John Wiley & Sons

Published: 2010-12-07

Total Pages: 536

ISBN-13: 1118035186

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Explores current and emerging applications of microbes as cancer-fighting agents WILEY SERIES IN BIOTECHNOLOGY AND BIOENGINEERING Anurag S. Rathore, Series Editor Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. In recent years, researchers have been working on a new strategy: developing microbes and microbial products that specifically attack cancer cells. This book breaks new ground in emerging cancer treatment modalities by presenting recent advances in the use of microorganisms and viruses as well as their products in cancer therapy. Seventeen chapters review the application of live microorganisms, high and low molecular weight products derived from microorganisms, and microbial products fused to cancertargeting molecules. In addition, the book highlights the benefits of a multi-target approach to destroy cancer cells. Readers will not only discover the results and significance of basic and clinical research, but also encouraging results from clinical trials. Emerging Cancer Therapy is divided into three sections: Section 1: Live/Attenuated Bacteria and Viruses as Anticancer Agents Section 2: Bacterial Products as Anticancer Agents Section 3: Patents on Bacteria/Bacterial Products as Anticancer Agents With chapters written by leading pioneers in microbial, biotech, and cancer research, Emerging Cancer Therapy is recommended for biotechnologists, microbiologists, clinical oncologists, medicinal chemists, and biochemists. Readers will not only learn the tremendous potential of microbial and biotechnological approaches to cancer therapy, but also discover new directions of research for effective drug discovery and development.

Bio-Engineering Approaches to Cancer Diagnosis and Treatment

Author: Azadeh Shahidian

Publisher: Academic Press

Published: 2020-05-14

Total Pages: 276

ISBN-13: 0128178108

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Bioengineering Approaches to Cancer Diagnosis and Treatment is written for an audience of senior undergraduate students and graduate students in mechanical, electrical and biomedical engineering fields and other professionals in medicine. It is ideally structured for teaching and for those who are working in cancer bioengineering or interdisciplinary projects. The book's authors bring a unique perspective from their expertise in immunology, nanobiomaterials and heat transfer. Topical coverage includes an introduction to the fundamentals of bioengineering and engineering approaches for cancer diagnosis, cancer treatment via case studies, and sections on imaging, immunotherapy, cell therapy, drug delivery, ultrasound and microfluidics in cancer treatment. Provides fully supported case studies relating to cancer diagnosis and therapy Pairs the basic fundamentals of engineering and biomedical engineering and applies them to the diagnosis of cancer

World Scientific Encyclopedia of Nanomedicine and Bioengineering II, The: Bioimplants, Regenerative Medicine, and Nano-Cancer Diagnosis and Phototherapy (a 4-Volume Set)

Author: Donglu Shi

Publisher: World Scientific Publishing Company Incorporated

Published: 2017-01-31

Total Pages: 1600

ISBN-13: 9789814667586

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This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine. An important aspect of this book set is the introduction of nanotechnology to the medical communities that are searching for new treatments of cancer. It may also break the barriers between the physical and medical sciences so that more MDs will be able to appreciate the new discoveries and establishments in medical diagnosis and therapy that will allow the effective handling of major clinical issues. This major reference publication will be important as the field of nanomedicine has been rapidly developing with a great deal of new information. It is anticipated that the research will soon advance into the pre-clinical stage. Therefore, this reference set can serve as valuable background information for future clinical studies.

Current Cancer Biomarkers

Author: Farhadul Islam

Publisher: Bentham Science Publishers

Published: 2023-01-30

Total Pages: 401

ISBN-13: 9815079379

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Current Cancer Biomarkers is a comprehensive review on the status of biological markers for various types of cancer. It aims to update readers on current developments on the subject. The contents are divided into 5 sections covering a wide range of biomarkers and their diagnostic applications. The range of tumour biomarkers referenced here gives insights into molecular mechanisms behind cancer, including initiation, development, progression, prognosis, response to the therapeutic modalities, recurrence, and point-of-care application to detect cancer. Key features - Introduction of the basic features of cancer markers - Comprehensive and updated coverage of potential and effective biomarkers including genomic, epigenomic, transcriptomic, proteomic, cellular and morphologic factors - Information on biomarkers in many types of cancers including breast cancer, colorectal cancer, skin cancer, leukemia, liver cancer and prostate cancer - Applications of biomarkers in cancer diagnosis - Structured contents with easy-to-understand sections and headings - References for advanced readers The updated information about different aspects of cancer markers in the experimental and clinical setting will enrich the reader's understanding of the disease. The information serves as a resource to help in better management of cancer patients and understanding cancer biology when planning medical research projects. The book is intended as a reference for a diverse audience: biomedical science students, medical students, academics, researchers, clinicians and multidisciplinary teams involved in cancer management and research.

Bioengineering and Cancer Stem Cell Concept

Author: Mirjana Pavlovic

Publisher: Springer

Published: 2015-12-22

Total Pages: 144

ISBN-13: 331925670X

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This book explores the role of cancer stem cells in the diagnosis, treatment, and cure of cancers. This book also tackles novel methodology for cancer stem cell marker identification, cancer stem cell respiration and metabolism, genetic and epigenetic mechanisms including DNA methylation, and mi-RNA assemble. It also emphasizes the role of Bioinformatics techniques, which provide a novel methodology for modeling cancer outcomes. The authors investigate the difference between cancer stem cells and normal stem cells, along with the concept of targeted cancer stem cell therapy. Although the theoretical explanations of cancer stem cell involvement in leukemia and solid cancers are controversial, there is now little doubt that cancer stem cells exist within otherwise heterogeneous cancer cell population. The brief examines the two leading theories, hierarchical and the stochastic/cancer stem cell model. Researchers, professors and advanced-level students focused on bioengineering and computer science will find this book to be a valuable resource. It is a very good source of critical references for understanding of this problem, and a useful tool for professionals in related fields.

World Scientific Encyclopedia Of Nanomedicine And Bioengineering Ii, The: Bioimplants, Regenerative Medicine, And Nano-cancer Diagnosis And Phototherapy (A 3-volume Set)

Author:

Publisher: World Scientific Publishing Company

Published: 2017-07-21

Total Pages: 802

ISBN-13: 9814667609

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This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine.An important aspect of this book set is the introduction of nanotechnology to the medical communities that are searching for new treatments of cancer. It may also break the barriers between the physical and medical sciences so that more MDs will be able to appreciate the new discoveries and establishments in medical diagnosis and therapy that will allow the effective handling of major clinical issues.This major reference publication will be important as the field of nanomedicine has been rapidly developing with a great deal of new information. It is anticipated that the research will soon advance into the pre-clinical stage. Therefore, this reference set can serve as valuable background information for future clinical studies.

Deployable Multimodal Machine Intelligence

Author: Hongliang Ren

Publisher: Springer Nature

Published: 2023-02-04

Total Pages: 589

ISBN-13: 9811959323

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This book highlights the principles, design and characterization of mechanically compliant soft and foldable robots. Traditional rigid robots with bulky footprints and complicated components prolong the design iteration and optimization for keyhole and minimally invasive transluminal applications. Therefore, there is an interest in developing soft and foldable robots with remote actuation, multimodal sensing and machine intelligence. This book discusses the use of foldable and cuttable structures to design biomimetic deployable soft robots, that can exhibit a fair number of motions with consistency and repeatability. It presents the overall design principles, methodology, instrumentation, metamorphic sensing, multi-modal perception, and machine intelligence for creating untethered foldable active structures. These robotic structures can generate a variety of motions such as wave induction, compression, inchworm, peristalsis, flipping, tumbling, walking, swimming, flexion/extension etc. Remote actuation can control motions along regular and irregular surfaces from proximal sides. For self-deployable medical robots, motion diversity and shape reconfiguration are crucial factors. Deployable robots, with the use of malleable and resilient smart actuators, hold this crucial advantage over their conventional rigid robot counterparts. Such flexible structures capable of being compressed and expanded with intelligence perceptions hold enormous potential in biomedical applications.

Career Development in Bioengineering and Biotechnology

Author: Guruprasad Madhavan

Publisher: Springer Science & Business Media

Published: 2009-01-07

Total Pages: 524

ISBN-13: 038776495X

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This indispensable guide provides a roadmap to the broad and varied career development opportunities in bioengineering, biotechnology, and related fields. Eminent practitioners lay out career paths related to academia, industry, government and regulatory affairs, healthcare, law, marketing, entrepreneurship, and more. Lifetimes of experience and wisdom are shared, including "war stories," strategies for success, and discussions of the authors’ personal views and motivations.