Bioengineering Approaches to Pulmonary Physiology and Medicine

Bioengineering Approaches to Pulmonary Physiology and Medicine PDF

Author: M.C.K. Khoo

Publisher: Springer Science & Business Media

Published: 2007-08-20

Total Pages: 256

ISBN-13: 0585349649

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As the current millennium steams towards a close, one cannot help but look with amazement at the incredible amount of progress that has been achieved in medicine in just the last few decades. A key contributing factor to this success has been the importation and blending of ideas and techniques from disciplines outside the traditional borders of medical science. In recent years, the most well-known example is the cross-pollination between molecular biology and medicine. Advances driven by this potent combination have spawned the vision of a future where cures based on gene therapy become commonplace. Yet, as we continue our search for "magic bullets" in the quest to eradicate disease, it important to recognize the value of other less-heralded interdisciplinary efforts that have laid a large part of the foundation of present-day medicine. In pulmonary medicine, the contribution from the bioengineers (a diverse collection of individuals cross-bred to various degrees in mathematical modeling and experimental physiology) has been larger and more sustained than in many other medical specialties. It is easy to point to the vast array of ventilators, blood-gas analyzers, oximeters, pulmonary function devices, and respiration monitors that are present in any modern clinical setting as solid evidence of the successful synergy between engineering science and pulmonary medicine. However, one must not forget the less tangible, but perhaps more important, contributions that have been derived from mathematical modeling and computer simulation, without which many of these modern instruments would not have come into existence.

Clinical and Biomedical Engineering in the Human Nose

Clinical and Biomedical Engineering in the Human Nose PDF

Author: Kiao Inthavong

Publisher: Springer Nature

Published: 2020-10-16

Total Pages: 308

ISBN-13: 9811567166

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This book explores computational fluid dynamics in the context of the human nose, allowing readers to gain a better understanding of its anatomy and physiology and integrates recent advances in clinical rhinology, otolaryngology and respiratory physiology research. It focuses on advanced research topics, such as virtual surgery, AI-assisted clinical applications and therapy, as well as the latest computational modeling techniques, controversies, challenges and future directions in simulation using CFD software. Presenting perspectives and insights from computational experts and clinical specialists (ENT) combined with technical details of the computational modeling techniques from engineers, this unique reference book will give direction to and inspire future research in this emerging field.

Physiological Control Systems

Physiological Control Systems PDF

Author: Michael C. K. Khoo

Publisher: Wiley-IEEE Press

Published: 1999-10-08

Total Pages: 344

ISBN-13: 9780780334083

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Many recently improved medical diagnostic techniques and therapeutic innovations have resulted from physiological systems modeling. This comprehensive book will help undergraduate and graduate students and biomedical scientists to gain a better understanding of how the principles of control theory, systems analysis, and model identification are used in physiological regulation. Ample Simulink? and MATLAB? examples throughout the text and posted at an IEEE FTP site will provide you with a hands-on approach for exploring modeling and analysis of biological control systems. You will learn about classical control theory and its application to physiological systems, and contemporary topics and methodologies shaping bioengineering research today. Discussions on the latest developments in system identification, optimal control, and nonlinear dynamical analysis will keep you up-to-date with recent bioengineering advances. From modeling and stability analysis to feedback control in physiological regulatory mechanisms, Physiological Control Systems provides an in-depth study of key bioengineering principles that is simply unmatched in the field. To obtain instructor material, please send an email to: [email protected]

Biomedical Engineering of Pancreatic, Pulmonary, and Renal Systems, and Applications to Medicine

Biomedical Engineering of Pancreatic, Pulmonary, and Renal Systems, and Applications to Medicine PDF

Author: Dhanjoo N. Ghista

Publisher: Elsevier

Published: 2023-05-15

Total Pages: 756

ISBN-13: 0323958850

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Biomedical Engineering Modeling of Pancreatic, Respiratory, and Renal Regulatory Systems, and their Medical Assessments addresses the need for biomedical engineering to provide physiological analysis of organ systems and their medical applications to help enable quantitative formulation of physiological systems and defining their functions and dysfunctions, leading to precision diagnostics of diabetes, lung diseases, and kidney failure, often in the form of non-dimensional indices. The book chapters also deal with treatment systems, namely automated insulin infusion systems, hemodialysis, and peritoneal dialysis. The book is formulated to solve many physiological, bioengineering, and medical problems. Covers foundational concepts of the emerging fields of quantitative physiology and computational medicine, developing the biomedical engineering modeling of three important organ systems: pancreas, lungs, and kidneys Provides readers with detailed understanding of novel biomedical engineering strategies in key areas, such as pancreatic system engineering, glucose-insulin regulatory system engineering, pulmonary system engineering, and renal system engineering Provides in-depth technical coverage of computational modeling techniques and applied mathematics for these important physiological systems, including differential equations and the associated MATLAB datasets for all applied diagnostic and treatment examples

Physiology for Engineers

Physiology for Engineers PDF

Author: Michael Chappell

Publisher: Springer

Published: 2021-05-12

Total Pages: 176

ISBN-13: 9783030397074

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This book provides an introduction to qualitative and quantitative aspects of human physiology. It examines biological and physiological processes and phenomena, including a selection of mathematical models, showing how physiological problems can be mathematically formulated and studied. It also illustrates how a wide range of engineering and physics topics, such as electronics, fluid dynamics, solid mechanics and control theory can be used to describe and understand physiological processes and systems. Throughout the text, there are introductions to measuring and quantifying physiological processes using both signaling and imaging technologies. This new edition includes updated material on pathophysiology, metabolism and the TCA cycle, as well as more advanced worked examples. This book describes the basic structure and models of cellular systems, the structure and function of the cardiovascular system, and the electrical and mechanical activity of the heart, and provides an overview of the structure and function of the respiratory and nervous systems. It also includes an introduction to the basic concepts and applications of reaction kinetics, pharmacokinetic modelling and tracer kinetics. It appeals to final year biomedical engineering undergraduates and graduates alike, as well as to practising engineers new to the fields of bioengineering or medical physics.

Identification of Nonlinear Physiological Systems

Identification of Nonlinear Physiological Systems PDF

Author: David T. Westwick

Publisher: John Wiley & Sons

Published: 2003-08-28

Total Pages: 284

ISBN-13: 9780471274568

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Significant advances have been made in the field since the previous classic texts were written. This text brings the available knowledge up to date. * Enables the reader to use a wide variety of nonlinear system identification techniques. * Offers a thorough treatment of the underlying theory. * Provides a MATLAB toolbox containing implementation of the latest identification methods together with an extensive set of problems using realistic data sets.

Modelling Methodology for Physiology and Medicine

Modelling Methodology for Physiology and Medicine PDF

Author: Ewart Carson

Publisher: Elsevier

Published: 2000-12-31

Total Pages: 421

ISBN-13: 0080511902

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Modelling Methodology for Physiology and Medicine offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modelling methodology that is widely applicable to physiology and medicine. The book opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. Builds upon and enhances the readers existing knowledge of modelling methodology and practice Editors are internationally renowned leaders in their respective fields

Nonlinear Dynamics in Physiology

Nonlinear Dynamics in Physiology PDF

Author: Mark Shelhamer

Publisher: World Scientific

Published: 2007

Total Pages: 367

ISBN-13: 9812700293

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This book provides a compilation of mathematical-computational tools that are used to analyze experimental data. The techniques presented are those that have been most widely and successfully applied to the analysis of physiological systems, and address issues such as randomness, determinism, dimension, and nonlinearity. In addition to bringing together the most useful methods, sufficient mathematical background is provided to enable non-specialists to understand and apply the computational techniques. Thus, the material will be useful to life-science investigators on several levels, from physiologists to bioengineer.Initial chapters present background material on dynamic systems, statistics, and linear system analysis. Each computational technique is demonstrated with examples drawn from physiology, and several chapters present case studies from oculomotor control, neuroscience, cardiology, psychology, and epidemiology. Throughout the text, historical notes give a sense of the development of the field and provide a perspective on how the techniques were developed and where they might lead. The overall approach is based largely on the analysis of trajectories in the state space, with emphasis on time-delay reconstruction of state-space trajectories. The goal of the book is to enable readers to apply these methods to their own research.