Biochips as Pathways to Drug Discovery

Biochips as Pathways to Drug Discovery PDF

Author: Andrew Carmen

Publisher: CRC Press

Published: 2006-10-19

Total Pages: 420

ISBN-13: 1420015605

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In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as bioc

Functional Protein Microarrays in Drug Discovery

Functional Protein Microarrays in Drug Discovery PDF

Author: Paul F. Predki

Publisher: CRC Press

Published: 2007-03-30

Total Pages: 482

ISBN-13: 1420009842

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An ideal text for biotechnologists, protein chemists, and biochemists, Functional Protein Microarrays in Drug Discovery explores all aspects of functional protein microarrays, including basic principles, methods, and applications. The book discusses the generation of functional protein content and describes both standard and state-of-the-art fabrication methods. It reviews current and next generation approaches to assay detection and presents a wide range of applications, from biomolecular interaction discovery and characterization to immune response profiling. The book also addresses several fundamental computational issues, bioinformatics and data analysis.

Phage Display In Biotechnology and Drug Discovery

Phage Display In Biotechnology and Drug Discovery PDF

Author: Sachdev S. Sidhu

Publisher: CRC Press

Published: 2015-03-16

Total Pages: 564

ISBN-13: 1439836507

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Phage Display in Biotechnology and Drug Discovery, Second Edition provides a comprehensive view of the impact and promise of phage display in drug discovery and biotechnology. Building on the success of its previous edition, the book discusses current theories, principles, and methods in the field and demonstrates applications for peptide phage dis

Functional Informatics in Drug Discovery

Functional Informatics in Drug Discovery PDF

Author: Sergey Ilyin

Publisher: CRC Press

Published: 2007-08-27

Total Pages: 160

ISBN-13: 9781420015683

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Integrating various technologies with informational systems provides vast improvements to the overall research and development that occur in the biopharmaceutical industry. One of the first books to explore this area, Functional Informatics in Drug Discovery examines all aspects of technology integration and information flow in a biopharmaceutical

Pathway Analysis for Drug Discovery

Pathway Analysis for Drug Discovery PDF

Author: Anton Yuryev

Publisher: Wiley

Published: 2008-09-29

Total Pages: 0

ISBN-13: 9780470107058

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This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in related fields.

Intelligent Materials

Intelligent Materials PDF

Author: Mohsen Shahinpoor

Publisher: Royal Society of Chemistry

Published: 2008

Total Pages: 555

ISBN-13: 0854043357

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Leading experts in the fields of chemistry, physics and engineering have contributed to this book highlighting the importance of smart material science in the 21st century

Digital Microfluidic Biochips

Digital Microfluidic Biochips PDF

Author: Krishnendu Chakrabarty

Publisher: CRC Press

Published: 2018-10-03

Total Pages: 228

ISBN-13: 1420008307

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Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.

Pharmacoeconomics

Pharmacoeconomics PDF

Author: Renee J. G. Arnold

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 259

ISBN-13: 1420084402

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The pharmaceutical industry is almost boundless in its ability to supply new drug therapies, but how does one decide which are the best medicines to use within restricted budgets? With particular emphasis on modeling, methodologies, data sources, and application to real-world dilemmas, Pharmacoeconomics: From Theory to Practice provides an introduc

Therapeutic Drug Monitoring

Therapeutic Drug Monitoring PDF

Author: Amitava Dasgupta

Publisher: Academic Press

Published: 2012-06-07

Total Pages: 469

ISBN-13: 0123854687

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Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential resource on the current practice of therapeutic drug monitoring in improving patient safety. Includes both the technical and clinical issues associated with therapeutic drug monitoring Discusses the utility of therapeutic drug monitoring of newer drugs such as antiretroviral agents, anticonvulsants, antidepressants etc. Provides up-to-date information on issues in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants Covers important content on the limitations of commercially available immunoassays (chemical tests) for therapeutic drug monitoring and additional analytical techniques

Biomedical Photonics Handbook

Biomedical Photonics Handbook PDF

Author: Tuan Vo-Dinh

Publisher: CRC Press

Published: 2003-03-26

Total Pages: 1864

ISBN-13: 0203008995

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A wide variety of biomedical photonic technologies have been developed recently for clinical monitoring of early disease states; molecular diagnostics and imaging of physiological parameters; molecular and genetic biomarkers; and detection of the presence of pathological organisms or biochemical species of clinical importance. However, available in