Biochemical Mechanisms of Paraquat Toxicity

Biochemical Mechanisms of Paraquat Toxicity PDF

Author: Anne Pomeroy Autor

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 250

ISBN-13: 0323159079

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Biochemical Mechanisms of Paraquat Toxicity presents the proceedings of the First Iowa Symposium on Toxic Mechanisms that was held from June 28-29, 1976. The symposium brought together a diverse group of investigators consisting of chemists, pharmacologists, pathologists, biochemists, and toxicologists from the United States, Canada, and Europe who have been interested in the mechanism of paraquat toxicity. The book includes papers on the following topics: the general features of toxic lung injury and observations with paraquat and diquat; electron transfer reactions of paraquat; the pathological effects of paraquat on the human lung; and the importance of oxygen and pulmonary alveolar surfactant in lung injury by paraquat. Other papers deal with the effects of paraquat on kidney and liver function in experimental animals; lipid peroxidation as a proposed mechanism for paraquat toxicity; pulmonary fibrosis as a consequence of paraquat toxicity; biochemical changes in lungs exposed to paraquat; effects of selenium deficiency on paraquat toxicity; and treatment for paraquat poisoning.

Paraquat Poisoning

Paraquat Poisoning PDF

Author: Chantal Bismuth

Publisher: Marcel Dekker

Published: 1995

Total Pages: 362

ISBN-13: 9780824793708

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This volume offers in-depth coverage of all important aspects of human paraquat poisoning, providing recent information on everything from the basic science of liquid peroxidation, to recent recommendations for prevention, diagnosis, prognosis and treatment. Perspectives from developed and developing countries are given. This work is intended for: medical and clinical toxicologists, organic, medicinal, agricultural and herbicide chemists; poison information specialists; public health, regulatory compliance and risk management officers; sanitarians; industrial hygienists; ecologists; and graduate-level and continuing-education students in these disciplines.

Hayes' Handbook of Pesticide Toxicology

Hayes' Handbook of Pesticide Toxicology PDF

Author:

Publisher: Academic Press

Published: 2010-02-15

Total Pages: 2407

ISBN-13: 0080922015

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The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.

Poisoning Diagnosis and Treatment

Poisoning Diagnosis and Treatment PDF

Author: J.A. Vale

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 237

ISBN-13: 940116763X

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In the last decade, the incidence of acute poisoning in the developed world has risen considerably, so that hospital admissions from this cause now repre~ sent a significant part of the work load of most medical units. The purpose of this book is to provide an up-to-date account of the diag nosis and treatment of all the clinically important poisons. Throughout the text the aim has been to emphasize the mechanisms of toxicity - wherever they are known - so that a rational approach to therapy may be devised. In addition, substantial chapters have been devoted to the psychiatric assess ment of self-poisoned patients and to the role of the laboratory. Two styles of presentation have been adopted. Certain topics are discussed in depth either because of their clinical importance or because recent data have become available concerning pathophysiology or treatment. In contrast, when subjects have been well described previously in general medical texts, for example, carbon monoxide poisoning, the discussion is far more brief and to the point. A similar style has been adopted with recently introduced drugs, where little is known about the effects in overdose. The value of cer tain chapters, especially those on poisonous plants and snake bites, has been enhanced by the inclusion of a large number of colour photographs.

Target Organ Toxicity

Target Organ Toxicity PDF

Author: Cohen

Publisher: CRC Press

Published: 1986-09-30

Total Pages: 256

ISBN-13: 9780849357763

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This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

Toxicological Study of Pesticides in Animals

Toxicological Study of Pesticides in Animals PDF

Author: T.S.S. Dikshith

Publisher: CRC Press

Published: 1990-12-19

Total Pages: 272

ISBN-13: 9780849369070

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This book discusses studies that have been conducted on various animal species. The book reviews the effects of pesticides through changes in behavior, the nature of morphological and biochemical lesions, as well as the tracking of the metabolic disposition of pesticides in target sites of an organism. In vitro studies provide information regarding cellular responses and biochemical lesions with pesticides. Toxicological profiles of pesticides are cited using different species of animals for in vivo and in vitro studies. This information should help scientists and decision-makers reach conclusions regarding the toxicological effects of pesticides on humans and the environment.