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Author: Clarence H. Suelter
Publisher: John Wiley & Sons
Published: 2009-09-25
Total Pages: 344
ISBN-13: 0470110996
DOWNLOAD EBOOK →Concerned with application of special instrumental methods to problems in biology. Describes the use of x-ray crystallography in biochemistry. Reviews the application of both transmission microscopy and scanning probe microscopy to biological problems. Discusses well-developed techniques used primarily in clinical laboratories.
Author: GHOSAL, SABARI
Publisher: PHI Learning Pvt. Ltd.
Published: 2018-09-01
Total Pages: 504
ISBN-13: 938747240X
DOWNLOAD EBOOK →This thoroughly revised edition of the book demonstrates principle and instrumentation of each technique routinely used in biotechnology. Like the previous edition, the second edition also follows non-mathematical approach. Three aspects of each technique including principle, methodology with knowledge of different parts of an instrument; and applications have now been discussed in the text. For the beginners, the book will help in building a strong foundation, starting from the preparation of solutions, extraction, separation and analysis of biomolecules to the characterisation by spectroscopic methods—the full gamut of biological analysis. NEW TO THE SECOND EDITION • Incorporates two new chapters on 'Radioisotope Tracer Techniques' and 'Basic Molecular Biology Techniques and Bioinformatics'. • Comprises a full chapter on 'Fermentation and Bioreactors' Design and Instrumentation' (the revised and updated version of Miscellaneous Methods of the previous edition). • Contains a number of pictorial illustrations, tables and worked-out examples to enhance students' understanding of the topics. • Includes chapter-end review questions. TARGET AUDIENCE • B.Sc./B.Tech (Biotechnology) • M.Sc./M.Tech (Biotechnology)
Author: Lauro Tatsuo Kubota
Publisher: Springer Nature
Published: 2021-11-25
Total Pages: 559
ISBN-13: 3030823814
DOWNLOAD EBOOK →This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis. Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.
Author: Abhilasha Shourie
Publisher: The Energy and Resources Institute (TERI)
Published: 2005-01-01
Total Pages: 424
ISBN-13: 8179935299
DOWNLOAD EBOOK →Bioanalytical Techniques form an integral part of applied biology and biomedical sciences. The various principles of bioanalytical techniques used in biomedical sciences, environmental studies, life sciences, pharmaceutical analysis, molecular biology, and biotechnological research are comprehensively discussed in this book. Analytical instrumentation is also explained in as concise a manner as possible. Microscopy, centrifugation, chromatography, electrophoresis, spectroscopy, and radioisotope and immunodiagnostic techniques are the main topics focussed in this book. Techniques in molecular biology and recombinant DNA technology have also been described in detail.
Author: Sabari Ghosal
Publisher: PHI Learning Pvt. Ltd.
Published: 2010-01-30
Total Pages: 308
ISBN-13: 9788120338555
DOWNLOAD EBOOK →Bioanalytical techniques are the integrated methods used in biological sciences and analytical chemistry. This comprehensive and well-written book is intended for those who wish to have a strong foundation in Biotech-nology. The book deals with various concepts, techniques, and instruments used in bioanalysis as well as their diverse practical applications. The text provides a good understanding of the general laboratory techniques, microscopic methods, various separation and spectroscopic techniques and many common issues of experimental design and data analysis. In addition, it discusses in detail various hydrodynamic techniques like sedimentation and centrifugation, pH, diffraction methods, bioreactors and, finally, the application of computers in fermentation technology. Key Features: Covers most bioanalytical techniques studied in Biotechnology. Provides a large number of diagrams to illustrate the concepts and methods. Contains Review Questions. This book is primarily intended as a text for undergraduate students of Biotechnology (B.Sc./B.Tech.) for their course on Methods of Instrumentation and Bioanalytical Techniques. Many concepts and techniques covered in the text are also prescribed for postgraduate courses (M.Sc./M.Tech.) in Biotechnology in most Indian universities. In addition, the book will be extremely useful as a reference for researchers, the faculty, and professionals in the field.
Author: Michael Zhou
Publisher: John Wiley & Sons
Published: 2011-03-31
Total Pages: 564
ISBN-13: 047092280X
DOWNLOAD EBOOK →This book provides useful information for bioanalytical / analytical scientists, analysts, quality assurance managers, and all personnel in bioanalytical laboratories through all aspects of bioanalytical technical and regulatory perspectives within bioanalytical operations and processes. Readers learn how to develop and implement strategies for routine, non-routine, and standard bioanalytical methods and on the entire equipment hardware and software qualification process. The book also gives guidelines on qualification of certified standards and in-house reference material as well as on people qualification. Finally, it guides readers through stressless internal and third party laboratory audits and inspections. It takes account to most national and international regulations and quality and accreditation standards, along with corresponding interpretation and inspection guides. The author elaborates on highly comprehensive content, making it easy not only to learn the subject but also to quickly implement the recommendations.
Author: Joshua B. Edel
Publisher: William Andrew
Published: 2013-03-19
Total Pages: 189
ISBN-13: 143773474X
DOWNLOAD EBOOK →Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necessary to carry out nanopore-based experiments for developing new devices. Includes application case studies for detection, identification and analysis of biomolecules and related functional nanomaterials Introduces the techniques of manufacturing solid state materials with functional nanopores Explains the use of nanopores in DNA sequencing and the wider range of applications from environmental monitoring to forensics
Author: Paolo Ugo
Publisher: Walter de Gruyter GmbH & Co KG
Published: 2021-02-08
Total Pages: 308
ISBN-13: 3110589168
DOWNLOAD EBOOK →The urgent need for rapid and reliable analytical tools suitable to perform a large number of high quality analyses of biological molecules has been dramatically stressed by the recent crisis caused by the COVID-19 pandemic. This book provides graduate students and young researchers with the elements of interdisciplinary knowledge necessary to apply the wide arsenal of bioanalytical devices and methods available today.
Author: Wenkui Li
Publisher: John Wiley & Sons
Published: 2013-09-03
Total Pages: 709
ISBN-13: 111867135X
DOWNLOAD EBOOK →Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results. Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling. Handbook of LC-MS Bioanalysis features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines: Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring The current understanding of regulations governing LC-MS bioanalysis Best practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest Experimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compounds With its focus on current bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.
Author: Chung Chow Chan
Publisher: John Wiley & Sons
Published: 2004-04-23
Total Pages: 320
ISBN-13: 047146371X
DOWNLOAD EBOOK →Validation describes the procedures used to analyze pharmaceutical products so that the data generated will comply with the requirements of regulatory bodies of the US, Canada, Europe and Japan. Calibration of Instruments describes the process of fixing, checking or correcting the graduations of instruments so that they comply with those regulatory bodies. This book provides a thorough explanation of both the fundamental and practical aspects of biopharmaceutical and bioanalytical methods validation. It teaches the proper procedures for using the tools and analysis methods in a regulated lab setting. Readers will learn the appropriate procedures for calibration of laboratory instrumentation and validation of analytical methods of analysis. These procedures must be executed properly in all regulated laboratories, including pharmaceutical and biopharmaceutical laboratories, clinical testing laboratories (hospitals, medical offices) and in food and cosmetic testing laboratories.
