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Bioactivity of Engineered Nanoparticles

Author: Bing Yan

Publisher: Springer

Published: 2017-08-17

Total Pages: 383

ISBN-13: 9811058644

This book brings together reviews from international experts who are exploring the biological activities of nanomaterials for medical applications or to better understand nanotoxicity. Topics include but are not limited to the following: 1) mechanistic understanding of nanostructure-bioactivity relationships; 2) the regulation of nanoparticles’ bioactivity by means of chemical modification; 3) the new methodologies and standard methods used to assess nanoparticles’ bioactivity; 4) the mechanisms involved in nanoparticle-biomolecule interactions and nanoparticle-cell interactions; and 5) biomedical applications of nanotechnology. The book will be a valuable resource for a broad readership in various subfields of chemical science, engineering, biology, environment, and medicine.

Engineered Nanoparticles and the Environment

Author: Baoshan Xing

Publisher: John Wiley & Sons

Published: 2016-08-29

Total Pages: 510

ISBN-13: 1119275830

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Details the source, release, exposure, adsorption, aggregation, bioavailability, transport, transformation, and modeling of engineered nanoparticles found in many common products and applications Covers synthesis, environmental application, detection, and characterization of engineered nanoparticles Details the toxicity and risk assessment of engineered nanoparticles Includes topics on the transport, transformation, and modeling of engineered nanoparticles Presents the latest developments and knowledge of engineered nanoparticles Written by world leading experts from prestigious universities and companies

Engineered Nanomaterials for Innovative Therapies and Biomedicine

Author: Hemen Sarma

Publisher: Springer Nature

Published: 2022-02-21

Total Pages: 463

ISBN-13: 3030829189

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Research on biomedical applications of nanomaterials has exhibited the rapidly evolving field of biomedical sciences by showing how effective they are in treatment. These particles hold considerable potential for biomedical applications. Work is ongoing, and the results suggest a possibility for a sustainable future for nanomaterials in both therapeutic and biomedical fields. This book highlights current and emerging applications, taking global research findings into consideration. We believe the focus on the identification and role of nanomaterial applications in therapeutic and biomedical sciences can lead to novel solutions in the fields. The chapters of this book are disseminated in a manner that can be readily adopted as sources for new and further study. The editors integrate advanced texts in their research that help graduate students, researchers and professors. Additionally, we believe that international readers will be able to make use of this book for reference purposes.

Biological Responses to Nanoscale Particles

Author: Peter Gehr

Publisher: Springer

Published: 2019-04-28

Total Pages: 344

ISBN-13: 9783030124601

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In this book the recent progress accumulated in studies of the interaction of engineered nanoparticles with cells and cellular constituents is presented. The focus is on manufacturing and characterization of nanosized materials, their interactions with biological molecules such as proteins, the mechanisms of transport across biological membranes as well as their effects on biological functions. Fundamental molecular and cellular aspects are in the foreground of the book. A further particularity is the interdisciplinary approach, including fields such as preparatory and analytical chemistry, biophysics and the physics of colloids, advanced microscopy and spectroscopy for in-situ detection of nanoparticles, cellular toxicology and nanomedicine. Nanoscale particles are known to exhibit novel and unprecedented properties that make them different from their corresponding bulk materials. As our ability to control these properties is further advanced, a huge potential to create materials with novel properties and applications emerges. Although the technological and economic benefits of nanomaterials are indisputable, concerns have also been raised that nanoscale structuring of materials might also induce negative health effects. Unfortunately, such negative health effects cannot be deduced from the known toxicity of the corresponding macroscopic material. As a result, there is a major gap in the knowledge necessary for assessing their risk to human health.

Characterisation of Engineered Nanoparticles and Their Interaction with Natural Biological and Non-biological Material

Author: Cameron S. Taylor

Publisher:

Published: 2014

Total Pages:

ISBN-13:

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The ELSI Handbook of Nanotechnology

Author: Chaudhery Mustansar Hussain

Publisher: John Wiley & Sons

Published: 2020-03-31

Total Pages: 580

ISBN-13: 1119592968

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This Handbook focuses on the recent advancements in Safety, Risk, Ethical Society and Legal Implications (ESLI) as well as its commercialization of nanotechnology, such as manufacturing. Nano is moving out of its relaxation phase of scientific route, and as new products go to market, organizations all over the world, as well as the general public, are discussing the environmental and health issues associated with nanotechnology. Nongovernmental science organizations have long since reacted; however, now the social sciences have begun to study the cultural portent of nanotechnology. Societal concerns and their newly constructed concepts, show nanoscience interconnected with the economy, ecology, health, and governance. This handbook addresses these new challenges and is divided into 7 sections: Nanomaterials and the Environment; Life Cycle Environmental Implications of Nanomanufacturing; Bioavailability and Toxicity of Manufactured Nanoparticles in Terrestrial Environments; Occupational Health Hazards of Nanoparticles; Ethical Issues in Nanotechnology; Commercialization of Nanotechnology; Legalization of Nanotechnology.

Biomedical Applications and Toxicity of Nanomaterials

Author: P. V. Mohanan

Publisher: Springer Nature

Published: 2023-05-08

Total Pages: 771

ISBN-13: 9811978344

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This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.

Nanotechnology for Biology and Medicine

Author: Gabriel A. Silva

Publisher: Springer Science & Business Media

Published: 2011-10-22

Total Pages: 242

ISBN-13: 038731296X

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This text book will bring together a mix of both internationally known and established senior scientists along side up and coming (but already accomplished) junior scientists that have varying expertise in fundamental and applied nanotechnology to biology and medicine.

Nanoengineering of Biomaterials

Author: Sougata Jana

Publisher: John Wiley & Sons

Published: 2021-12-10

Total Pages: 1063

ISBN-13: 3527832106

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In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications untersucht ein Expertenteam von Chemikern in prägnanter Form die Synthese, Charakterisierung und Freisetzung von Wirkstoffmolekülen in vitro und in vivo, die pharmakokinetische Aktivität, pharmakodynamische Aktivität und die biomedizinischen Anwendungen verschiedener Arten von nanotechnologisch hergestellten Biomaterialien. Zudem werden die neuesten Entwicklungen in diesem Bereich anhand von aktuellen Materialien präsentiert. Dieses Werk ist eine Sammlung von wertvollen und leicht zugänglichen Referenzquellen für Forscher in der Materialchemie und verwandten Forschungsgebieten. Unter Verwendung eines funktionsorientierten Ansatzes werden organische und anorganische Ausgangsverbindungen zur Herstellung biologischer Systeme genutzt, die als Gerüste, Mizellen, Dendrimere und andere Verabreichungssysteme dienen. Nanoengineering of Biomaterials vermittelt aktuelle Erkenntnisse aus der Chemie und der Materialwissenschaft, die sich leicht auf biomedizinische Systeme übertragen lassen. Darüber hinaus bietet das Werk: * Eine gründliche Einführung in die Verabreichung von Therapeutika durch Alginat-Nanopartikel und Nanomaterialien auf Chitosan-Basis in biologischen Anwendungen * Eine umfassende Betrachtung von nanostrukturiertem Carrageen als Wirkstoffträger, Gellangummi-Nanopartikeln bei der Wirkstoffverabreichung und Guargummi-Nanopartikeln bei der Verabreichung bioaktiver Moleküle * Eine praktische Erörterung von proteinbasierten Nanopartikeln bei der Wirkstoffverabreichung, festen Lipid-Nanopartikeln als Wirkstoffträger und auf den pH-Wert reagierenden Nanopartikeln in der Therapie * Eine grundlegende Untersuchung von auf bestimmte Stimuli reagierenden Nanoträgern bei der gezielten Wirkstoffverabreichung Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications ist nicht nur perfekt für Fachleute in der pharmazeutischen Chemie, Materialwissenschaft, Polymerchemie, den Biowissenschaften und der Medizinalchemie geeignet, sondern ist auch eine unverzichtbare Quelle für Biologen und Bioingenieure auf der Suche nach einem umfassenden Nachschlagewerk, das sich mit der Übertragbarkeit der Materialchemie und Nanotechnologie auf die Biomedizin beschäftigt.

Biological Synthesis of Nanoparticles and Their Applications

Author: L Karthik

Publisher: CRC Press

Published: 2019-12-06

Total Pages: 463

ISBN-13: 0429560257

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Biological Synthesis of Nanoparticles and Their Applications gives insight into the synthesis of nanoparticles utilizing the natural routes. It demonstrates various strategies for the synthesis of nanoparticles utilizing plants, microscopic organisms like bacteria, fungi, algae and so forth. It orchestrates interdisciplinary hypothesis, ideas, definitions, models and discoveries associated with complex cell of the prokaryotes and eukaryotes. Highlights: Discusses biological approach towards the nanoparticle synthesis Describes the role of nanotechnology in the field of medicine and its medical devices Covers application and usage of the chemicals at the molecular level to act as catalysts and binding products for both organic and inorganic Chemical Reactions Reviews application in physics such as solar cells, photovoltaics and other usage Microorganisms can aggregate and detoxify substantial metals because of different reductase enzymes, which can diminish metal salts to metal nanoparticles. The readers after going through this book will have detailed account of mechanism of bio-synthesis of nanoparticles.