Bacteriophage T4 and Its Relatives. a Series of Critical Reviews

Bacteriophage T4 and Its Relatives. a Series of Critical Reviews PDF

Author: Jim D. Karam

Publisher: Biomed Central Limited

Published: 2010-10

Total Pages: 0

ISBN-13: 9780954027872

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Phage T4 is a large DNA virus that infects and multiplies in the bacterium Escherichia coli (E. coli) and certain other bacteria that normally inhabit the mammalian gut. Relatives of T4 are widely distributed in nature and propagate in a variety of bacterial species in marine and terrestrial environments. The genomes of these phages encode an enormous biochemical complexity that rival the complexity exhibited by the much larger genomes of their bacterial hosts. Collectively, T4 and its relatives have proven to be powerful systems for research into the genetic and biochemical mechanisms that control the replication, expression and evolution of DNA genomes as well as viral assembly. This book contains a collection of review articles covering research in these areas over the last 20 years. The articles appeared online as a thematic series in 2010 in BioMed Central's Virology Journal. They are reprinted here in hardcopy as a convenient source of the most current reviewed information on this family of phages for instructors and trainees in the microbial and molecular biological sciences.

Introduction to Genetic Analysis

Introduction to Genetic Analysis PDF

Author: Anthony J.F. Griffiths

Publisher: Macmillan

Published: 2008

Total Pages: 872

ISBN-13: 9780716768876

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Provides an introduction to genetic analysis. This book covers contemporary genetics, and helps students understand the essentials of genetics, featuring various experiments, teaching them how to analyze data, and how to draw their own conclusions

Molecular Biology of Bacteriophage T4

Molecular Biology of Bacteriophage T4 PDF

Author: Jim D. Karam

Publisher: ASM Press

Published: 1994

Total Pages: 648

ISBN-13:

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This new text highlights the value of this biological system as a research and teaching tool. The book is a sequel to the 1983 edition and is organized into 6 major sections: DNA metabolism, regulation of gene expression, morphogenesis, structure of selected proteins, host–phage interactions, and laboratory experiments in T4 molecular genetics. Since T4 has played a central role in the development of molecular biology as an academic discipline, the themes presented in this book provide a framework for designing graduate and undergraduate courses in prokaryotic genetics and biochemistry.

The Biology of Nonspecific DNA Protein Interactions

The Biology of Nonspecific DNA Protein Interactions PDF

Author: Arnold Revzin

Publisher: CRC Press

Published: 1990-08-27

Total Pages: 278

ISBN-13: 9780849361777

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This important publication addresses the interactions of proteins with nonspecific binding sites on DNA as they play critical roles in fundamental cellular processes such as transcription, DNA replication, and recombination. The book presents current reviews of the biochemistry of representative nonspecific DNA-protein systems, and of their physiological functions. It includes chapters on the techniques used to characterize the complexes, on their thermodynamic properties, and on the role of nonspecific binding as gene regulatory proteins search for specific target sites on the chromosome. Systems considered include the effects of nonspecific binding in regulation of the lactose operon of Escherichia coli, the T4 bacteriophage gene 32 protein, the E. coli single strand binding (SSB) protein and recA protein, eukaryotic SSB's and histone-DNA complexes. The book presents those proteins displaying multiple modes of DNA binding as participants in more than one cellular process. This monograph combines rigorous descriptions of new findings for these important systems with provocative interpretations of the biological significance of the results. It is of great value to researchers ranging from graduate students to senior scientists in the areas of biochemistry, microbiology and molecular/cell biology.

Phage and the Origins of Molecular Biology

Phage and the Origins of Molecular Biology PDF

Author: John Cairns

Publisher: Firefly Books

Published: 1992

Total Pages: 386

ISBN-13: 9780879695958

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This is an expanded edition of the landmark collection of 35 essays by pioneers of molecular biology that was first published in 1966 as a 60th birthday tribute to Max Delbruck. The book was hailed as "[introducing] into the literature of science, for the first time, a self-conscious historical element in which the participants in scientific discovery engage in writing their own chronicle. As such, it is an important document in the history of biology..." (Journal of History of Biology). This new edition includes Gunther Stent's obituary of Max Delbruck, two commentaries on issues raised in the book reprinted from Scientific American and Science, and a new preface in which John Cairns reflects on the book's creation and molecular biology's "age of innocence."

Bacteriophages

Bacteriophages PDF

Author: David R. Harper

Publisher: Springer Nature

Published: 2021-01-30

Total Pages: 1376

ISBN-13: 3319419862

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This first major reference work dedicated to the mannifold industrial and medical applications of bacteriophages provides both theoretical and practical insights into the emerging field of bacteriophage biotechnology. The book introduces to bacteriophage biology, ecology and history and reviews the latest technologies and tools in bacteriophage detection, strain optimization and nanotechnology. Usage of bacteriophages in food safety, agriculture, and different therapeutic areas is discussed in detail. This book serves as essential guide for researchers in applied microbiology, biotechnology and medicine coming from both academia and industry.

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