-PDF Download- Autoimmune Liver Diseases Autoimmune Hepatitis Pbc And Psc An Issue Of Clinics In Liver Disease E Book EBOOK

AUTOIMMUNE LIVER DISEASES: AUTOIMMUNE HEPATITIS, PBC, AND PSC, An Issue of Clinics in Liver Disease, E-Book

Author: David Bernstein

Publisher: Elsevier Health Sciences

Published: 2023-11-10

Total Pages: 225

ISBN-13: 044312146X

In this issue of Clinics in Liver Disease, guest editor Dr. David E. Bernstein brings his considerable expertise to the topic of Autoimmune Hepatitis Including PBC and PSC. The three main immune disorders that involve the liver are AIH, primary biliary cholangitis, and primary sclerosing cholangitis. As these autoimmune diseases can share symptoms, it is important for the hepatologist to have clinical knowledge of each and understand their differences and similarities. This issue addresses these variants and provides the reader with important information relating to pathology, diagnosis, and treatment. Contains 15 relevant, practice-oriented topics including autoimmune hepatitis: epidemiology, subtypes, and presentation; diagnosis of autoimmune hepatitis; treatment of autoimmune hepatitis including transplant; diagnostic tests in primary sclerosing cholangitis: serology, elastography, imaging; post-transplant management and complications of AIH, PBC, and PSC, including disease recurrence; and more. Provides in-depth clinical reviews on autoimmune hepatitis, including PBC and PSC, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Autoimmune Liver Diseases: Autoimmune Hepatitis, Pbc, and Psc, an Issue of Clinics in Liver Disease: Volume 28-1

Author: David Bernstein

Publisher: Clinics: Internal Medicine

Published: 2024-02-28

Total Pages: 0

ISBN-13: 9780443121456

DOWNLOAD EBOOK →

Primary Biliary Cholangitis , An Issue of Clinics in Liver Disease, E-Book

Author: Binu V. John

Publisher: Elsevier Health Sciences

Published: 2022-10-21

Total Pages: 249

ISBN-13: 0323972950

DOWNLOAD EBOOK →

In this issue of Clinics in Liver Disease, guest editor Dr. John V. Binu brings his considerable expertise to the topic of Primary Biliary Cholangitis. PBC leads to inflammation and scarring of the small bile ducts, and, if untreated, can lead to cirrhosis and liver failure. In this issue, top experts provide a state-of-the-art review of diagnosis and treatment for this chronic, progressive liver disorder. Contains 13 practice-oriented topics including genetics of primary biliary cholangitis; prognostic scoring systems in PBC; overlap syndromes and PBC; non-invasive evaluation of fibrosis and portal hypertension in PBC; treatment of PBC: first- and second-line therapies; novel therapies for PBC; and more. Provides in-depth clinical reviews on primary biliary cholangitis, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease

Author: Cynthia Levy

Publisher: Elsevier Health Sciences

Published: 2013-05-28

Total Pages: 244

ISBN-13: 1455771996

DOWNLOAD EBOOK →

Dr. Levy is a key leader in the field of hepatology , and she has enlisted authors who are top experts in their fields to submit state-of-the-art clinical reviews on cholestatic liver diseases. Articles are devoted to genetic determinants of cholestasis, nuclear receptors as drug targets, drug-induced cholestasis, primary sclerosing cholangitis, therapeutic advances in primary biliary cirrhosis, overlap syndromes, autoimmune sclerosing cholangitis, secondary sclerosing cholangitis, Focus is also on familial cholestasis, allagile syndrome and other hereditary causes of cholestasis, Systemic causes of cholestasis, advances in pathogenesis and treatment of pruritus, care of the cholestatic patient, and transplantation for cholestatic diseases . Readers will come away with a full overview of the diagnosis and treatment of cholestatic liver diseases.

Autoimmune Hepatitis

Author: Gideon M. Hirschfield

Publisher: Springer Science & Business Media

Published: 2011-12-02

Total Pages: 249

ISBN-13: 160761569X

DOWNLOAD EBOOK →

With a focus on practical patient related issues, Autoimmune Hepatitis: A Guide for Practicing Clinicians serves as a useful practical, and much needed, resource for all those physicians presented with managing patients diagnosed with autoimmune hepatitis, both acutely and over the long term. It provides a basis for clinicians to understand the etiology of the disease, as well as special circumstances where management dilemmas often arise. Emphasis is given to providing management advice of immediate use to clinicians, something not presently offered by other larger general texts. The chapters are written by those with an expertise and training in this field and include the most up to date information. The book will be of great value to Gastroenterologists, Hepatologists, and Internists at all levels who see patients presenting with autoimmune hepatitis.

Advances in Cholestatic Liver Diseases, An issue of Clinics in Liver Disease

Author: Cynthia Levy

Publisher: Elsevier Health Sciences

Published: 2016-01-07

Total Pages: 225

ISBN-13: 0323429920

DOWNLOAD EBOOK →

Dr. Levy has secured the field’s top experts to offer the latest clinical reviews on cholestatic liver disease. The issue will include articles devoted to The Gut-Liver Axis; Update on Genetics in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis; New thoughts on IgG4 Associated Cholangitis; Cancer Risk and Surveillance in PSC; Novel Therapies for PBC; and Liver transplantation for Cholestatic Liver Diseases, to name a few. Dr. Levy’s issue will be the most current authority on cholestatic liver disease.

Consultations in Liver Disease, An Issue of Clinics in Liver Disease

Author: Steven L. Flamm

Publisher: Elsevier Health Sciences

Published: 2014-12-24

Total Pages: 241

ISBN-13: 0323354610

DOWNLOAD EBOOK →

Dr. Flamm has invited a group of distinguished hepatologists to provide insight into the assessment of a variety of scenarios where clinical judgment based on experience and published literature is an invaluable addition to the care of individual patients. Articles included in the issue address the following topics: Evaluation and Management of Portal Vein Thrombosis, Liver Disease in the HIV patient, Hepatocellular Carcinoma, Evaluation of Renal Insufficiency in the Cirrhotic Patient, Contemporary Management of Autoimmune Hepatitis, Diagnosis and Treatment of Overlap Syndromes, Ins and Outs of Liver Imaging for the Gastroenterologist, Contemporary Assessment of Hepatic Fibrosis, A Primer on Liver Transplantation Immunosuppressive Agents for the Gastroenterologist, Evaluation of Jaundice in the Hospitalized Patient, Liver Disease in the Adolescent, Evaluation and Management of Hemochromatosis and How and When to Administer Hepatitis A and B Virus Vaccinations. These are all common contemporary reasons for consultations for Gastroenterologists and Hepatologists and this issue will address the issues in a pragmatic way.

Autoimmune Liver Disease

Author: James Neuberger

Publisher: John Wiley & Sons

Published: 2020-01-28

Total Pages: 421

ISBN-13: 1119532620

DOWNLOAD EBOOK →

Ein praxisorientierter Leitfaden zu autoimmunen Lebererkrankungen, Pathogenese, Diagnose und Management. Autoimmune Liver Disease Management and Clinical Practice erläutert alles Wissenswerte zum aktuellen Forschungsstand autoimmuner Lebererkrankungen und legt dabei den Schwerpunkt auf Diagnose und Behandlung. Nach einer ausführlichen Darstellung der heutigen Erkenntnisse in der Immunologie in Verbindung mit der Autoimmunität der Leber werden die vier wichtigsten autoimmunen Lebererkrankungen bei Erwachsenen und Kindern erläutert, einschließlich Management, Rolle von Lebertransplantationen, erprobte Ansätze des Patientenmanagements und Empowerment-Ansätze. Die Autoren, Experten des Fachgebiets, untersuchen im Detail autoimmune Lebererkrankungen und geben Kliniker Handreichungen zur Patientenunterstützung. Die folgenden Themenkomplexe werden unter anderem ausführlich behandelt: - Die vier autoimmunen Lebererkrankungen, deren Diagnose und Behandlungsoptionen. - Einsatz (und Missbrauch) von Autoantikörpern bei Diagnose und Behandlung. - Rolle und Zeitpunkt von Lebertransplantationen und die Auswirkung auf wiederkehrende autoimmune Lebererkrankungen und De-novo-Autoimmunhepatitis. - Optimales Patientenmanagement und patientenbezogene Pflege. Dieses Referenzwerk zeigt umfassend, im Detail und mit alltäglichem Praxisbezug die jüngsten Entwicklungen beim Management von Lebererkrankungen und richtet sich an Ärzte, Pflegepersonal und Experten im Gesundheitswesen.

Autoimmune Liver Disease

Author: H.-P. Dienes

Publisher: Springer Science & Business Media

Published: 2005-07-12

Total Pages: 332

ISBN-13: 9781402028946

DOWNLOAD EBOOK →

Autoimmune processes in the liver can cause severe damage and destruction leading to cirrhosis and liver failure. The clinical spectrum of autoimmune liver disease is very wide, and diagnostic difficulties often stand at the beginning of the patient’s medical career. While in autoimmune hepatitis immunosuppressive therapy has long been shown to be life-saving, therapeutic progress is small in primary biliary cirrhosis and questionable in primary sclerosing cholangitis. New approaches to treatment will be needed in the future, but require better understanding of the pathogenesis of the underlying disease process. This book, the proceedings of Falk Symposium 142 on 'Autoimmune Liver Disease’ held in Freiburg, Germany, on 12–13 October 2004 (Part I of the Gastroenterology Week Freiburg), describes possible mechanisms of pathogenesis, discusses diagnostic criteria and takes up controversies concerning treatment options. In view of the relatively frequent manifestation of autoimmune hepatitis in childhood in particular, paediatric aspects of autoimmune liver disease, and the role of liver transplantation, are given prominence.

Immunology and Liver

Author: M.P. Manns

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 426

ISBN-13: 9401140006

DOWNLOAD EBOOK →

In 1992, the Falk Symposium No. 70 dealt with the topic `Immunology and Liver'. At that time basic mechanisms of immunology as well as immunopathogenetic mechanisms in viral and autoimmune liver diseases were discussed. Now, 7 years later, the Falk Symposium No. 114, held in Basel, Switzerland, October 20-21 1999 (Part I of the Basel Liver Week 1999), focused on immunology in autoimmune liver diseases. In the first section basic mechanisms of autoimmunity are presented, including the relevance of superantigens and the role of apoptosis. A further topic is the latest developments concerning animal models for autoimmune diseases. Recently the International Autoimmune Hepatitis Group newly defined and reclassified the syndrome of autoimmune hepatitis. Autoimmune hepatitis is now identified and studied in all parts of the world, including Asia and South America. A special variant of autoimmune hepatitis was identified as one organ manifestation of the autoimmune polyendocrine syndrome type 1, a genetic disease caused by mutations in a single transcription factor. Drug- and hepatitis-virus induced immune mediated liver diseases may serve as models for nonhepatic immune mediated disorders. DNA technology has increased our knowledge of the immunogenetic background of autoimmune liver diseases. Among the cholestatic immune mediated liver diseases, significant progress has been made concerning primary biliary cirrhosis, in particular regarding the identification of mitochondrial antigens and the characterisation of the immune reactions directed at them. The involvement of infectious agents in PBC as well as the definition of overlap syndromes is a particular focus for basic and clinical research in this area. Concerning the therapy of autoimmune liver diseases, corticosteroids and azathioprin remain the state of the art for autoimmune hepatitis, while bile acids have become well established in treatment of primary biliary cirrhosis as well as primary sclerosing cholangitis. New drugs in the future will include topical steroids such as budesonide and new immunosuppressive agents like mofetil/mycophenolate. Liver transplantation is the treatment of choice for end stage liver diseases; all autoimmune liver diseases are among the best candidates for liver transplantation. Hopefully, new therapeutic strategies based on the results obtained from experimental models will become everyday clinical practice in the next decade. Therefore this symposium concludes with a discussion.