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Atlas of Zebrafish Development

Author: Robert Bryson-Richardson

Publisher: Academic Press

Published: 2012

Total Pages: 240

ISBN-13: 0123740169

Zebrafish are widely considered an excellent model system for vertebrate development. The embryo is transparent, thereby enabling visualization and use of labelling and transgenic approaches. Moreover, because of the ease of inducing new mutations in zebrafish and similarity with the human genome, this organism may be used effectively for disease studies. For example, mutant zebrafish are being utilized for testing drugs that will combat a range of human diseases, from Alzheimer's and cancer to kidney failure and congenital heart disease. For the first time, this atlas provides the research community with a complete reference for zebrafish anatomy spanning the early embryo all the way to adulthood. The authors employ the technique of optical projection tomography (OPT), and offer a series of sections in multiple planes from each sample. The contents are organized by developmental stages, with over 200 images that contain annotations describing anatomical structures relevant to development. In addition, chapters feature explanatory text that highlights major developments in the zebrafish during each stage. Provides the first comprehensive anatomical resource that covers all regions of zebrafish anatomy from the larval period to adulthood The over 200 images include explanatory notes Each chapter contains a concise description of key anatomical features that factor in zebrafish development Despite many years of use as a model system, until now there has never been a guide to zebrafish at the larval stage The book's website contains a database of over 10k sections from different regions as well as 3D images that are interactive

Atlas of Zebrafish Development

Author: Robert Bryson-Richardson

Publisher: Academic Press

Published: 2017-11-13

Total Pages: 240

ISBN-13: 9780128103456

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Zebrafish are widely considered an excellent modelsystem for vertebrate development. The embryo is transparent, thereby enabling visualization and use of labelling and transgenic approaches. Moreover, because of the ease of inducing new mutations in zebrafish and similarity with the human genome, this organism may be used effectively for disease studies. For example, mutant zebrafish are being utilized for testing drugs that will combat a range of human diseases, from Alzheimer's and cancer to kidney failure and congenital heart disease. For the first time, this atlas provides the research community with a complete reference for zebrafish anatomy spanning the early embryo all the way to adulthood. The authors employ the technique of optical projection tomography (OPT), and offer a series of sections in multiple planes from each sample. The contents are organized by developmental stages, with over 200 images that contain annotations describing anatomical structures relevant to development. In addition, chapters feature explanatory text that highlights major developments in the zebrafish during each stage. Provides the first comprehensive anatomical resource that covers all regions of zebrafish anatomy from the larval period to adulthoodThe over 200 images include explanatory notesEach chapter contains a concise description of key anatomical features that factor in zebrafish developmentDespite many years of use as a model system, until now there has never been a guide to zebrafish at the larval stageThe book's website contains a database of over 10k sections from different regions as well as 3D images that are interactive"

Atlas of Early Zebrafish Brain Development

Author: Dr. Thomas Mueller

Publisher: Academic Press

Published: 2015-11-18

Total Pages: 258

ISBN-13: 0124172865

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Atlas of Early Zebrafish Brain Development: A Tool for Molecular Neurogenetics, Second Edition, remains the only neuroanatomical expression atlas of important genetic and immunohistochemical markers of this vertebrate model system. It represents a key reference and interpretation matrix for analyzing expression domains of genes involved in Zebrafish brain development and neurogenesis, and serves as a continuing milestone in this research area. This updated volume provides in-situ hybridized and immunostained preparations of complete series of brain sections, revealing markers of the fundamental stages in the life history of neuronal cells in very high quality preparations and photographic plates. Specific additions to this edition include documentation on the distribution of neurons expressing GABA, dopamine and serotonin, material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon, new theories on the early organization of the telencephalon and thalamus, and integration of a comparative perspective on the mid- and hindbrain. Documentation on the distribution of neurons expressing GABA, dopamine and serotonin Material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon New theories about the early organization of the telencephalon and thalamus Integration of a comparative perspective on the mid- and hindbrain

The Zebrafish

Author: Joseph A. Holden

Publisher: Cambridge University Press

Published: 2012

Total Pages: 157

ISBN-13: 1107621348

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The zebrafish (Danio rerio) is a valuable and common model for researchers working in the fields of genetics, oncology and developmental sciences. This full-color atlas will aid experimental design and interpretation in these areas by providing a fundamental understanding of zebrafish anatomy. Over 150 photomicrographs are included and can be used for direct comparison with histological slides, allowing quick and accurate identification of the anatomic structures of interest. Hematoxylin and eosin stained longitudinal and transverse sections demonstrate gross anatomic relationships and illustrate the microscopic anatomy of major organs. Unlike much of the current literature, this book is focused exclusively on the zebrafish, eliminating the need for researchers to exclude structures that are only found in other fish.

Atlas of Early Zebrafish Brain Development

Author: Thomas Mueller

Publisher: Gulf Professional Publishing

Published: 2005-08-08

Total Pages: 204

ISBN-13: 9780444517388

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"The book introduces the reader to the field and shows principles of vertebrate brain development and neurogenesis. It will also be of great value to investigators of other model organisms such as frog, chick, and mouse."--BOOK JACKET.

Color Atlas of Zebrafish Histology and Cytology

Author: Jinxing Lin

Publisher: Springer Nature

Published: 2022-10-21

Total Pages: 314

ISBN-13: 981169852X

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This book elucidates the tissue structure and cell composition of the organs of zebrafish at the microscopic, ultrastructural and molecular levels. The distribution of important macromolecular substances is shown and the morphological relationship between different components is analyzed. The book is divided into 15 chapters and contains more than 700 structural photos, all of which are original experimental pictures of the research group. It shows the histological panorama of the whole zebrafish both in cross and longitudinal sections and covers and interprets the tissues and organs of zebrafish in detail, including oropharynx, taste buds, pharyngeal teeth, liver, etc. A brief text description of the structure and function meaning is available for every picture to facilitate the audience understanding the theoretical knowledge more vivid and concrete. In addition, the 3D reconstruction of the main organs of zebrafish is completed by computer-aided technology, and the three-dimensional morphology of the organs is displayed in an intuitive form. This book provides a reference for postgraduates and researchers in anatomy, biology, animal medicine, animal science, aquaculture, developmental biology, medicine, and experimental animals.

Zebrafish

Author: Christiane Nusslein-Volhard

Publisher: Oxford University Press

Published: 2002-09-19

Total Pages: 342

ISBN-13: 9780199638086

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The zebrafish has become one of the most important model organisms to study biological processes within a living body. As a vertebrate that has many of the strengths of invertebrate model systems, it offers numerous advantages to researchers interested in many aspects of embryonic development, physiology and disease. This book not only provides a complete set of instructions that will allow researchers to establish the zebrafish in their laboratory. It also gives a broad overview of commonly used methods and a comprehensive collection of protocols describing the most powerful techniques.

Neuroanatomy of the Zebrafish Brain

Author: Mario F. Wulliman

Publisher: Birkhäuser

Published: 2019-05-13

Total Pages: 0

ISBN-13: 9783034898522

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gene-expression patterns in the zebrafish correspond well The zebrafish belongs to the teleostean family of with the neuromeric model of Puelles and Rubenstein cyprinids (minnows), which includes other neurobiologi (1993) is very encouraging for further research in this cally well investigated species such as goldfish (Carassius model system, which holds the promise of revealing fun auratus) and carp (e. g. Cyprinus carpio). damental neurogenetic patterns and mechanisms in ver In a recent taxonomic revision (Barman, 1991), all spe tebrates. cies of the genus Brachydanio were reassigned to the genus Danio. Thus, the current species designation of the zebrafish is Danio (formerly Brachydanio) rerio (Hamil ton-Buchanan, 1822). As a cyprinid, the zebrafish belongs Generation of zebrafish mutants via saturation mutagenesis to the large group of ostariophysan teleosts (6000 species, The goal of saturation mutagenesis is to identify most - if Lauder and Liem, 1983). Most ostariophysans are charac not all- genes affecting early animal development and to terized by a sophisticated apparatus - the Weberian ossi understand their hierarchical, regulative role during de des - to transmit sound from the swim bladder to the velopment (for reviews, see: Mullins and Ntisslein-Vol inner ear. The ostariophysans belong to the most derived hard, 1993; Solnica-Krezel et aI. , 1994). This approach has group of teleosts, the euteleosts (17000 species), which recently been applied to the zebrafish system, and the re have three more basic teleostean outgroups, the oste sults are impressive.

Laboratory Studies of Vertebrate and Invertebrate Embryos

Author: Gary C. Schoenwolf

Publisher: Benjamin-Cummings Publishing Company

Published: 2001

Total Pages: 372

ISBN-13:

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The eighth edition of this widely respected volume continues the tradition of introducing laboratory studies of developmental biology with its broad coverage, copious illustrations and detailed descriptions of a wide range of developing stages. Unique in its combination of a detailed atlas with interesting exercises on living embryos, it also contains complete instructions for additional experimental studies that include state-of-the-art research approaches. The eighth edition adds a new chapter on the development of the mouse embryo, many new illustrations, seven new advanced hands-on studies and a glossary.

Development and Engineering of Dopamine Neurons

Author: Jeroen Pasterkamp

Publisher: Springer Science & Business Media

Published: 2009-12-16

Total Pages: 143

ISBN-13: 1441903224

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Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections. In the last decade, studies on gene expression and development have further increased the knowledge of this neuronal population and have unmasked a new level of complexity. The start of the molecular dissection of the mdDA system has been marked by the cloning and characterization ofNurrl and Pitx3. These transcription factors were shown to have a critical function during mdDA development. These initial studies have been followed by the identification of many other proteins, which have a crucial function in the creation of a dopamine neuron permissive region, induction of precursors, induction of terminaldifferent- tion and finally maintenance of the mdDA neuronal pool.