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Aspergillus and Penicillium in the Post-genomic Era

Author: Ronald P. de Vries

Publisher: Caister Academic Press Limited

Published: 2016

Total Pages: 0

ISBN-13: 9781910190395

Genome sequencing has affected studies into the biology of all classes of organisms and this is certainly true for filamentous fungi. The level with which biological systems can be studied since the availability of genomes and post-genomic technologies is beyond what most people could have imagined previously. The fungal genera Aspergillus and Penicillium contain some species that are amongst the most widely used industrial microorganisms and others that are serious pathogens of plants, animals and humans. These genera are also at the forefront of fungal genomics with many genome sequences available and a whole genus genome sequencing project in progress for Aspergillus. This book highlights some of the changes in the studies into these fungi, since the availability of genome sequences. The contributions vary from insights in the taxonomy of these genera, use of genomics for forward genetics and genomic adaptations, to specific stories addressing virulence, carbon starvation, sulphur metabolism, feruloyl esterases, secondary metabolism and pH modulation, to the development of novel methodology for use in parallel to genome sequencing. It therefore provides a taste of the current status of research in Penicillium and Aspergillus and a promise of many more things to come. An essential reference for everyone working with Aspergillus and Penicillium and other filamentous fungi and the book is also recommended reading for everyone with an interest in fungal genomics.

Aspergillus Systematics in the Genomic Era

Author: Robert A. Samson

Publisher:

Published: 2007

Total Pages: 224

ISBN-13:

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Aspergillus in the genomic era

Author: János Varga

Publisher: BRILL

Published: 2023-08-28

Total Pages: 334

ISBN-13: 9086866352

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Aspergillus is among the economically most important fungal genera. Aspergillus species are used in the fermentation industry for the production of various enzymes, organic acids and pharmaceutically important compounds, and in Oriental food fermentations. At the same time, Aspergilli can cause opportunistic infections, and produce a range of secondary metabolites also known as mycotoxins which are harmful to humans and animals. Due to its importance in biotechnology, medicine and foods, Aspergilli are in the forefront of studies dealing with various aspects of fungi. This is well illustrated by the fact that projects aiming at sequencing the genomes of nine species are in progress. In this book, some aspects of the biology of this genus are covered, including the biotechnological importance of Aspergilli, their role in mycotoxin contamination of food products including grapes and coffee products, and implications of biodiversity of Aspergillus populations for agriculture. Among the clinical aspects, the role of Aspergilli in eye infections, the mechanisms of antifungal drug resistance and their molecular identification in the clinical setting are covered. Several chapters deal with the genomic aspects of Aspergilli, including the genomics of pigment biosynthesis, extracellular enzyme production, aflatoxin biosynthesis and the identification of genes taking part in sexual processes. Additional chapters cover the variability and inheritance of mycoviruses in Aspergilli and multilocus approaches are given to clarify the evolutionary history of the genus. Finally, a new taxonomic classification of the various Aspergillus sections is given based on multilocus sequence data.

Aspergillus

Author: Masayuki Machida

Publisher: Caister Academic Press Limited

Published: 2010

Total Pages: 0

ISBN-13: 9781904455530

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In-depth reviews of molecular systematics, bioinformatics, systems biology, transcriptional regulation, genetics, genomics, secondary metabolism, ecology, development, and industrial applications.

Advances in Applied Microbiology

Author:

Publisher: Academic Press

Published: 2017-07-18

Total Pages: 210

ISBN-13: 0128120495

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Advances in Applied Microbiology, Volume 100 continues to be one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. This latest release includes specific chapters on a variety of topics, most notably, Current interventions for controlling pathogenic Escherichia coli, Microbial ecology and process technology of sourdough fermentation, Diversity, Application, and Synthetic Biology of Industrially Important Aspergillus Fungi, and Advances in the Microbial Ecology of Biohydrometallurgy. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays and the role of polyamines in bacterial growth and biofilm formation. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Contains contributions from leading authorities Informs and updates on all the latest developments in the field Includes discussions on protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays and more

Encyclopedia of Microbiology

Author: Thomas M. Schmidt

Publisher: Academic Press

Published: 2019-09-11

Total Pages: 3248

ISBN-13: 0128117370

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Encyclopedia of Microbiology, Fourth Edition, Five Volume Set gathers both basic and applied dimensions in this dynamic field that includes virtually all environments on Earth. This range attracts a growing number of cross-disciplinary studies, which the encyclopedia makes available to readers from diverse educational backgrounds. The new edition builds on the solid foundation established in earlier versions, adding new material that reflects recent advances in the field. New focus areas include `Animal and Plant Microbiomes’ and ‘Global Impact of Microbes`. The thematic organization of the work allows users to focus on specific areas, e.g., for didactical purposes, while also browsing for topics in different areas. Offers an up-to-date and authoritative resource that covers the entire field of microbiology, from basic principles, to applied technologies Provides an organic overview that is useful to academic teachers and scientists from different backgrounds Includes chapters that are enriched with figures and graphs, and that can be easily consulted in isolation to find fundamental definitions and concepts

Environmental Toxicology

Author: Luis M. Botana

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2018-05-22

Total Pages: 283

ISBN-13: 3110442043

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Organic and inorganic chemicals frequently exhibit toxic, mutagenic, carcinogenic, or sensitizing properties when getting in contact with the environment. This comprehensive introduction discusses risk assessment and analysis, environmental fate, transport, and breakdown pathways of chemicals, as well as methods for prevention and procedures for decontamination.

Fungi in Extreme Environments: Ecological Role and Biotechnological Significance

Author: Sonia M. Tiquia-Arashiro

Publisher: Springer

Published: 2019-07-22

Total Pages: 626

ISBN-13: 3030190307

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Over the last decades, scientists have been intrigued by the fascinating organisms that inhabit extreme environments. These organisms, known as extremophiles, thrive in habitats which for other terrestrial life-forms are intolerably hostile or even lethal. Based on such technological advances, the study of extremophiles has provided, over the last few years, ground-breaking discoveries that challenge the paradigms of modern biology. In the new bioeconomy, fungi in general, play a very important role in addressing major global challenges, being instrumental for improved resource efficiency, making renewable substitutes for products from fossil resources, upgrading waste streams to valuable food and feed ingredients, counteracting life-style diseases and antibiotic resistance through strengthening the gut biota, making crop plants more robust to survive climate change conditions, and functioning as host organisms for production of new biological drugs. This range of new uses of fungi all stand on the shoulders of the efforts of mycologists over generations. The book is organized in five parts: (I) Biodiversity, Ecology, Genetics and Physiology of Extremophilic Fungi, (II) Biosynthesis of Novel Biomolecules and Extremozymes (III) Bioenergy and Biofuel synthesis, and (IV) Wastewater and biosolids treatment, and (V) Bioremediation.

Genetics and Biotechnology

Author: J. Philipp Benz

Publisher: Springer Nature

Published: 2020-10-28

Total Pages: 452

ISBN-13: 3030499243

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This fully revised third edition includes up-to-date topics and developments in the field, which has made tremendous strides since the publication of the second edition in 2004. Many novel techniques based on Next Generation Sequencing have sped up the analysis of fungi and major advances have been made in genome editing, leading to a deeper understanding of the genetics underlying cellular processes as well as their applicability. At the same time, the relevance of fungi is unbroken, both due to the serious threats to human health and welfare posed by fungal pests and pathogens, and to the many benefits that fungal biotechnology can offer for diverse emerging markets and processes that form the basis of the modern bioeconomy. With regard to these advances, the first section of this volume, Genetics, illustrates the basic genetic processes underlying inheritance, cell biology, metabolism and “lifestyles” of fungi. The second section, Biotechnology, addresses the applied side of fungal genetics, ranging from new tools for synthetic biology to the biotechnological potential of fungi from diverse environments. Gathering chapters written by reputed scientists, the book represents an invaluable reference guide for fungal biologists, geneticists and biotechnologists alike.

The Fungal Kingdom

Author: Joseph Heitman

Publisher: John Wiley & Sons

Published: 2020-07-10

Total Pages: 1136

ISBN-13: 1555819583

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Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.