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Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products

Author: Marco Rito-Palomares

Publisher: Springer

Published: 2017-07-18

Total Pages: 191

ISBN-13: 3319593099

This comprehensive and unique text presents a full overview of downstream processing useful for those new to the concept as well as professionals with experience in the area. The history and theoretical principles of Aqueous Two-Phase Systems (ATPS) are covered in depth. Information on ATPS characterization and application is included, and ATPS equilibria and system parameters that have significant effect on partition behavior are studied. Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products addresses specific applications of ATPS for the recovery and partial purification of high molecular weight compounds such as proteins, nucleic acids and polysaccharides, particulate bioproducts such as cells and organelles and low molecular weight compounds. Non-conventional strategies involving ATPS such as affinity systems, continuous liquid-liquid fractionation stages and the recovery from plant extracts are presented. Economic analysis of the application of ATPS in comparison to other fractionation techniques, particularly liquid chromatography, is considered, as are opportunity and current trends in the ATPS research area. Each chapter utilizes the contributors' experimental expertise in traditional and non-conventional ATPS strategies, as well as analysis of areas of opportunity and perspectives on the development and future applications of ATPS in both the lab and larger scale operations. The result is a thorough and singular overview of ATPS which has not been matched by any other text on the market.

Bioprocess Intensification

Author: Dirk Holtmann

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2024-07-01

Total Pages: 386

ISBN-13: 3110760339

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Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs.

Liquid-Phase Extraction

Author: Colin F. Poole

Publisher: Elsevier

Published: 2019-08-29

Total Pages: 818

ISBN-13: 0128169125

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Liquid Phase Extraction thoroughly presents both existing and new techniques in liquid phase extraction. It not only provides all information laboratory scientists need for choosing and utilizing suitable sample preparation procedures for any kind of sample, but also showcases the contemporary uses of sample preparation techniques in the most important industrial and academic project environments, including countercurrent chromatography, pressurized-liquid extraction, single-drop Microextraction, and more. Written by recognized experts in their respective fields, it serves as a one-stop reference for those who need to know which technique to choose for liquid phase extraction. Used in conjunction with a similar release, Solid Phase Extraction, it allows users to master this crucial aspect of sample preparation. Defines the current state-of-the-art in extraction techniques and the methods and procedures for implementing them in laboratory practice Includes extensive referencing that facilitates the identification of key information Aimed at both entry-level scientists and those who want to explore new techniques and methods

Envisioning the Future of Industrial Bioprocesses Through Biorefinery

Author: Sónia Patrícia Marques Ventura

Publisher: Frontiers Media SA

Published: 2021-04-07

Total Pages: 79

ISBN-13: 2889666700

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Biotechnology Annual Review

Author: M. Raafat El-Gewely

Publisher: Elsevier

Published: 2006-08-08

Total Pages: 422

ISBN-13: 0080465463

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Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists’ knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, recent advances in all-protein chromophore technology- to topics that are focused on coencapsulation of hepatocytes and bone marrow cell. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training. Includes over 80 illustrations and photographs Discusses the recent developments in biodegradable synthetic polymers Offers a detailed discussion on emerging options in protein bioseparation

Liquid Biphasic System

Author: Pau Loke Show

Publisher: Elsevier

Published: 2020-11-28

Total Pages: 330

ISBN-13: 0128223987

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Downstream bioprocesses have a significant role to play in the creation of a sustainable bio-based economy, enabling the creation of new products and systems from the more sustainable bioprocessing of natural products. Liquid Biphasic System: Fundamentals, Methods, and Applications in Bioseparation Technology explores in detail the fundamental processes and applications of this new separation system, aiding understanding of the basic principles of the technique and offering constructive criticisms on the latest findings. Including coverage of the background, principles, mechanisms, and applications, Liquid Biphasic System addresses how to adapt the technology for the purification of useful compounds with greater cost efficiency and greener processing. It is essential reading for bioprocess engineers, biochemical engineers, biosystem engineers, chemists and microbiologists working in the fields of bioprocessing. Researchers, scientists, and engineers concerned with the selection and evaluation of alternative bioseparation processes will find the book particularly useful. Provides information and examples of advanced separations in a single source Includes detailed descriptions of novel bioseparation systems Covers the latest technologies related to advanced liquid–liquid separation and their applications in various industries

Food Engineering Handbook, Two Volume Set

Author: Theodoros Varzakas

Publisher: CRC Press

Published: 2014-12-12

Total Pages: 944

ISBN-13: 1466582278

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Food Engineering Handbook, Two-Volume Set provides a stimulating and up-to-date review of food engineering phenomena. It also addresses the basic and applied principles of food engineering methods used in food processing operations around the world. Combining theory with a practical, hands-on approach, this set examines the thermophysical properties and modeling of selected processes such as chilling, freezing, and dehydration, and covers the key aspects of food engineering, from mass and heat transfer to steam and boilers, heat exchangers, diffusion, and absorption. Comprised of Food Engineering Handbook: Food Engineering Fundamentals and Food Engineering Handbook: Food Process Engineering, this comprehensive resource: Explains the interactions between different food constituents that might lead to changes in food properties Describes the characterization of the heating behavior of foods, their heat transfer, heat exchangers, and the equipment used in each food engineering method Discusses rheology, fluid flow, evaporation, distillation, size reduction, mixing, emulsion, and encapsulation Provides case studies of solid–liquid and supercritical fluid extraction and food behaviors Explores fermentation, enzymes, fluidized-bed drying, and more Presenting cutting-edge information on new and emerging food engineering processes, Food Engineering Handbook, Two-Volume Set offers a complete reference on the fundamental concepts, modeling, quality, safety, and technologies associated with food engineering and processing operations today.

The Science and Application of Aqueous Two-Phase Systems and Liquid-Liquid Phase Separation in Biotechnology and Bioengineering

Author: John Paul Frampton

Publisher: Frontiers Media SA

Published: 2020-01-13

Total Pages: 117

ISBN-13: 288963356X

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The phase separation of incompatible liquids has been a topic of significant importance in chemical and industrial engineering for many years. Well-understood examples of this phenomenon include the phase separation of oil with water and the phase separation of non-polar organic solvents with water. Similar behavior is observed when aqueous solutions of two or more incompatible polymers or polymers and salts are mixed. In these mixtures (referred to as aqueous two-phase systems), the separated phases are composed mostly of water. Aqueous two-phase systems have been used extensively for the extraction of high-value biological products from mixtures of biological materials. In recent years, aqueous two-phase systems have also found increased use as materials for streamlining and improving the capabilities of cell and molecular assays, and for the design of advanced cell culture systems. Similar behavior of biological materials in living systems has also been observed, with emerging roles in cell physiology.

Food Engineering Handbook

Author: Theodoros Varzakas

Publisher: CRC Press

Published: 2014-11-24

Total Pages: 654

ISBN-13: 1482261685

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Food Engineering Handbook: Food Process Engineering addresses the basic and applied principles of food engineering methods used in food processing operations around the world. Combining theory with a practical, hands-on approach, this book examines the thermophysical properties and modeling of selected processes such as chilling, freezing, and dehy

Food Waste Recovery

Author: Charis M. Galanakis

Publisher: Academic Press

Published: 2020-12-01

Total Pages: 562

ISBN-13: 0128225920

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Food Waste Recovery: Processing Technologies, Industrial Techniques, and Applications, Second Edition provides information on safe and economical strategies for the recapture of value compounds from food wastes while also exploring their re-utilization in fortifying foods and as ingredients in commercial products. Sections discuss the exploration of management options, different sources, the Universal Recovery Strategy, conventional and emerging technologies, and commercialization issues that target applications of recovered compounds in the food and cosmetics industries. This book is a valuable resource for food scientists, technologists, engineers, chemists, product developers, researchers, academics and professionals working in the food industry. Covers food waste management within the food industry by developing recovery strategies Provides coverage of processing technologies and industrial techniques for the recovery of valuable compounds from food processing by-products Explores the different applications of compounds recovered from food processing using three approaches: targeting by-products, targeting ingredients, and targeting bioactive applications