ANTIRETROVIRAL THERAPY FOR HIV INFECTION IN INFANTS AND CHILDREN: TOWARDS UNIVERSAL ACCESS: Recommendations for a Public Health Approach
Author: World Health Organization
Publisher:
Published: 2022
Total Pages: 0
ISBN-13:
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Antiretroviral therapy for HIV infection in infants and children
Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection
Author: World Health Organization
Publisher:
Published: 2016
Total Pages: 429
ISBN-13: 9789241549684
DOWNLOAD EBOOK →These guidelines provide guidance on the diagnosis of human immunodeficiency virus (HIV) infection, the use of antiretroviral (ARV) drugs for treating and preventing HIV infection and the care of people living with HIV. They are structured along the continuum of HIV testing, prevention, treatment and care. This edition updates the 2013 consolidated guidelines on the use of antiretroviral drugs following an extensive review of evidence and consultations in mid-2015, shared at the end of 2015, and now published in full in 2016. It is being published in a changing global context for HIV and for health more broadly.
Ethics and Drug Resistance: Collective Responsibility for Global Public Health
Author: Euzebiusz Jamrozik
Publisher: Springer
Published: 2021-08-21
Total Pages: 448
ISBN-13: 9783030278762
DOWNLOAD EBOOK →This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century.
WHO Child Growth Standards
Author: World Health Organization
Publisher: World Health Organization
Published: 2007
Total Pages: 238
ISBN-13: 9241547189
DOWNLOAD EBOOK →A comprehensive review of the uses and interpretation of anthropometric references undertaken by WHO in the early 1990s concluded that new growth curves were needed to replace the existing international reference. To develop new standards, a multi-country study was carried out to collect primary growth data and related information from 8440 healthy breastfed infants and young children from diverse ethnic backgrounds and cultural settings (Brazil, Ghana, India, Norway, Oman, and the USA). The first set of growth standards (length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age) was published in April 2006. This report presents the second set of growth standards (head circumference-for-age, arm circumference-for-age, triceps skinfold-for-age, and subscapular skinfold-for-age). The standards depict normal early childhood growth under optimal environmental conditions and can be used to assess children everywhere, regardless of ethnicity socioeconomic status and type of feeding. This report will be useful to pediatricians and other healthcare providers, nutritionists, policy makers, researchers, national institutes of health, schools of medicine, and professional associations. Companion volume: WHO Child Growth Standards: Length/Height-for-age Weight-for-age Weight-for-length Weight-for-height and Body Mass Index-for age. Methods and Development
Pocket Book of Hospital Care for Children
Author: World Health Organization
Publisher: World Health Organization
Published: 2013
Total Pages: 442
ISBN-13: 9241548371
DOWNLOAD EBOOK →The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.
Guidelines on HIV and Infant Feeding 2010
Author: World Health Organization
Publisher:
Published: 2010
Total Pages: 49
ISBN-13: 9789241599535
DOWNLOAD EBOOK →Significant programmatic experience and research evidence regarding HIV and infant feeding have accumulated since WHO's recommendations on infant feeding in the context of HIV were last revised in 2006. In particular, evidence has been reported that antiretroviral (ARV) interventions to either the HIV-infected mother or HIV-exposed infant can significantly reduce the risk of postnatal transmission of HIV through breastfeeding. This evidence has major implications for how women living with HIV might feed their infants, and how health workers should counsel these mothers. Together, breastfeeding and ARV intervention have the potential to significantly improve infants' chances of surviving while remaining HIV uninfected. While the 2010 recommendations are generally consistent with the previous guidance, they recognize the important impact of ARVs during the breastfeeding period, and recommend that national authorities in each country decide which infant feeding practice, i.e. breastfeeding with an ARV intervention to reduce transmission or avoidance of all breastfeeding, should be promoted and supported by their Maternal and Child Health services. This differs from the previous recommendations in which health workers were expected to individually counsel all HIV-infected mothers about the various infant feeding options, and it was then for mothers to decide between them. Where national authorities promote breastfeeding and ARVs, mothers known to be HIV-infected are now recommended to breastfeed their infants until at least 12 months of age. The recommendation that replacement feeding should not be used unless it is acceptable, feasible, affordable, sustainable and safe (AFASS) remains, but the acronym is replaced by more common, everyday language and terms. Recognizing that ARVs will not be rolled out everywhere immediately, guidance is given on what to do in their absence.
WHO Recommendations on the Diagnosis of HIV Infection in Infants and Children
Author: World Health Organization
Publisher:
Published: 2010
Total Pages: 55
ISBN-13: 9789241599085
DOWNLOAD EBOOK →Worldwide, in 2008, an estimated 430 000 [240 000-610 000] new infections due to the human immunodeficiency virus (HIV) occurred in children, of which 90% were acquired through mother-to-child transmission (MTCT) of HIV. Of the 430 000 new infections, between 280 000 and 360 000 were acquired during labour and in the pre-partum period. Of the remaining new infections, the majority were acquired during breastfeeding. In infants who acquire HIV around the time of delivery, disease progression occurs very rapidly in the first few months of life, often leading to death. To enable antiretroviral (ARV) prophylaxis to be given to infants as soon as possible after birth, all infants should have their HIV exposure status known at birth. As not all mothers are given HIV tests, very few HIV-exposed infants are identified and very few infants are known to be gaining access to early diagnosis, the necessary prerequisite to'timely' initiation of antiretroviral therapy (ART). Currently, only an estimated 15% of HIV-exposed infants needing testing are tested in the first two months of life. Recently published data confirming dramatic survival benefits for infants started on ART as early as possible after the diagnosis of HIV, prompted a review of the World Health Organization (WHO) paediatric treatment guidelines. In June 2008, new guidance was issued, which recommends prompt initiation of ART in infants diagnosed with HIV infection. In order to identify those infants who will need immediate ART, early confirmation of HIV infection is required. In November 2008, a meeting was convened to review recommendations by WHO for the diagnostic testing of HIV infection in infants and children. The meeting brought together the guideline review group that had developed the initial recommendations in 2005. The guideline review group followed the grading of recommendations assessment, development and evaluation (GRADE) approach in reviewing the recommendations for early detection of HIV infection according to the current WHO Guidelines for Guidelines. This document contains the new recommendations. The full document, including GRADE evidence profiles and the factors that have been taken into account in the group's decision-making with respect to the strength of the recommendations, is available in the annexes.
Updated recommendations on HIV prevention, infant diagnosis, antiretroviral initiation and monitoring
Author:
Publisher: World Health Organization
Published: 2021-03-17
Total Pages: 84
ISBN-13: 9240022236
DOWNLOAD EBOOK →These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral therapy (ART) among people living with HIV who are being treated for tuberculosis. WHO is currently in the process of collating all HIV normative guidance developed since 2016 in order to publish the third edition of the consolidated HIV guidelines in July 2021. This updated version will include the new clinical guidance presented here.
Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring
Author: World Health Organization
Publisher: World Health Organization
Published: 2021-07-16
Total Pages: 592
ISBN-13: 9240031596
DOWNLOAD EBOOK →These consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring bring together existing and new clinical and programmatic recommendations across different ages, populations and settings, bringing together all relevant WHO guidance on HIV produced since 2016. It serves as an update to the previous edition of the consolidated guidelines on HIV. These guidelines continue to be structured along the continuum of HIV care. Information on new combination prevention approaches, HIV testing, ARV regimens and treatment monitoring are included. There is a new chapter on advanced HIV disease that integrates updated guidance on the management of important HIV comorbidities, including cryptococcal disease, histoplasmosis and tuberculosis. The chapter on general HIV care, contains a new section on palliative care and pain management, and up to date information on treatment of several neglected tropical diseases, such as visceral leishmaniasis and Buruli ulcer. New recommendations for screening and treating of cervical pre-cancer lesions in women living with HIV are also addressed in this chapter. Guidance on service delivery was expanded to help the implementation and strengthening the HIV care cascade. Importantly, this guidance emphasizes the need for differentiated approaches to care for people who are established on ART, such as reduced frequency of clinic visits, use of multi-month drug dispensing and implementation of community ART distribution. The adoption of these efficiencies is essential to improve the quality of care of people receiving treatment and reduce the burden on health facilities, particularly in resource limited settings.
