Disease Control Priorities, Third Edition (Volume 6)

Disease Control Priorities, Third Edition (Volume 6) PDF

Author: King K. Holmes

Publisher: World Bank Publications

Published: 2017-11-06

Total Pages: 1027

ISBN-13: 1464805253

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Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Mechanisms of antibiotic resistance

Mechanisms of antibiotic resistance PDF

Author: Jun Lin

Publisher: Frontiers Media SA

Published: 2015-06-01

Total Pages: 226

ISBN-13: 2889195260

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Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Antimicrobial Resistance

Antimicrobial Resistance PDF

Author: World Health Organization

Publisher:

Published: 2014

Total Pages: 232

ISBN-13: 9789241564748

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Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

Antibiotic Resistance

Antibiotic Resistance PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2011-01-10

Total Pages: 496

ISBN-13: 0309156114

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Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Antimicrobial Resistance

Antimicrobial Resistance PDF

Author: J. Todd Weber

Publisher: Karger Medical and Scientific Publishers

Published: 2010-01-01

Total Pages: 185

ISBN-13: 3805593236

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Preventing, controlling and treating drug-resistant infections is one of the major challenges in modern medicine. Antimicrobial Resistance goes beyond simple definitions and microbiological data to fully explore this rapidly changing area, describing evidence for effective interventions, costs, treatment strategies and directions for future research. Each chapter provides essential background and examines the evidence for an important aspect of prevention and control, treatment strategy or policy decision. Prevention and control strategies are analyzed for inappropriate antimicrobial use, fluoroquinolone-resistant organisms, health-care associated infections and parasitic diseases. Furthermore, treatment strategies for changing resistance patterns are explored for community-acquired pneumonia during an influenza pandemic and infections with community-associated MRSA, extended-spectrum beta-lactamase producing organisms and fungi. Data for policy making are presented in articles that detail the costs of antimicrobial-resistant infections in healthcare settings and the threat of resistance with the introduction of antiretroviral therapy for large populations in the developing world. These reviews show where interventions, surveillance and research will be most useful in the future. Antimicrobial Resistance is an invaluable contribution for infectious disease physicians and public health officials who are interested in the prevention of antimicrobial-resistant infections.

Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine

Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine PDF

Author: National Academies Of Sciences Engineeri

Publisher: National Academies Press

Published: 2022-07-20

Total Pages:

ISBN-13: 9780309269452

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The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.

Antimicrobial Resistance

Antimicrobial Resistance PDF

Author: Yashwant Kumar

Publisher: BoD – Books on Demand

Published: 2019-05-02

Total Pages: 144

ISBN-13: 178985783X

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The discovery of antibiotics was considered a milestone in health sciences and became the mainstay of antimicrobial therapy to treat and control bacterial infections. However, its utility has subsequently become limited, due to the emergence and spread of antimicrobial resistance among different bacterial species, which has emerged as a global threat. The development and spread of antimicrobial resistance have been attributed to many factors, including indiscriminate use of antibiotics in the healthcare and livestock industries. The present scenario of antibiotic resistance urgently requires interventions in terms of development of newer antimicrobials, evaluation of alternative therapies, and formulation of stringent policies to curb indiscriminate use of antimicrobials. This book highlights the importance and development of antimicrobial resistance in zoonotic, environmental and food bacteria, including the significance of candidate alternative therapies.

Combating Antimicrobial Resistance

Combating Antimicrobial Resistance PDF

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2018-01-08

Total Pages: 173

ISBN-13: 0309466520

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As of 2017, the emergence and spread of antimicrobial resistance continues unabated around the world, leaving devastating health and economic outcomes in its wake. Those consequences will multiply if collaborative global action is not taken to address the spread of resistance. Major drivers of antimicrobial resistance in humans have been accelerated by inappropriate antimicrobial prescribing in health care practices; the inappropriate use of antimicrobials in livestock; and the promulgation of antibiotic resistance genes in the environment. To explore the issue of antimicrobial resistance, the Forum of Microbial Threats planned a public workshop. Participants explored issues of antimicrobial resistance through the lens of One Health, which is a collaborative approach of multiple disciplines - working locally, nationally, and globally - for strengthening systems to counter infectious diseases and related issues that threaten human, animal, and environmental health, with an end point of improving global health and achieving gains in development. They also discussed immediate and short-term actions and research needs that will have the greatest effect on reducing antimicrobial resistance, while taking into account the complexities of bridging different sectors and disciplines to address this global threat. This publication summarizes the presentations and discussions from the workshop.