The Resistance Phenomenon in Microbes and Infectious Disease Vectors

The Resistance Phenomenon in Microbes and Infectious Disease Vectors PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2003-03-26

Total Pages: 333

ISBN-13: 0309168309

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The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Antimicrobial Susceptibility Testing Protocols

Antimicrobial Susceptibility Testing Protocols PDF

Author: Richard Schwalbe

Publisher: CRC Press

Published: 2007-05-22

Total Pages: 430

ISBN-13: 1420014498

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The clinical microbiology laboratory is often a sentinel for the detection of drug resistant strains of microorganisms. Standardized protocols require continual scrutiny to detect emerging phenotypic resistance patterns. The timely notification of clinicians with susceptibility results can initiate the alteration of antimicrobial chemotherapy and

Treating Infectious Diseases in a Microbial World

Treating Infectious Diseases in a Microbial World PDF

Author: National Research Council

Publisher: National Academies Press

Published: 2006-01-03

Total Pages: 102

ISBN-13: 0309180686

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Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Antibiotics in Laboratory Medicine

Antibiotics in Laboratory Medicine PDF

Author: Victor Lorian

Publisher: Lippincott Williams & Wilkins

Published: 2005

Total Pages: 924

ISBN-13: 9780781749831

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Implement the most current science and practice in antimicrobial research. Now, find the newest approaches for evaluating the activity, mechanisms of action, and bacterial resistance to antibiotics with this completely updated, landmark reference. Turn to this comprehensive reference for groundbreaking evidence on the molecular link between chemical disinfectants, sterilants, and antibiotics. On the latest methods for detecting antibacterial resistance genes in the clinical laboratory, and antivirogram use to select the most active antiviral components against your patient's HIV.

Antimicrobial Resistance

Antimicrobial Resistance PDF

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1998-06-13

Total Pages: 128

ISBN-13: 0309060842

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Antibiotic resistance is neither a surprising nor a new phenomenon. It is an increasingly worrisome situation, however, because resistance is growing and accelerating while the world's tools for combating it decrease in power and number. In addition, the cost of the problemâ€"especially of multidrug resistanceâ€"in terms of money, mortality, and disability are also rising. This book summarizes a workshop on antimicrobial resistance held by the Forum on Emerging Infections. The goal of the Forum on Emerging Infections is to provide an opportunity for representatives of academia, industry, government, and professional and interest groups to examine and discuss scientific and policy dilemmas of common interest that are specifically related to research on and the prevention, detection, and management of emerging infections. Organized as a topic-by-topic synthesis of presentations and exchanges during the workshop, the book highlights lessons learned, delineates a range of pivotal issues and the problems they raise, and proposes some simplified ideas about possible responses.

The Use of Drugs in Food Animals

The Use of Drugs in Food Animals PDF

Author: National Research Council

Publisher: National Academies Press

Published: 1999-01-12

Total Pages: 276

ISBN-13: 0309175771

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The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.

Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine

Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine PDF

Author: National Academies Of Sciences Engineeri

Publisher: National Academies Press

Published: 2022-07-20

Total Pages:

ISBN-13: 9780309269452

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The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.

Antibiotics toward Gram Positive Cocci: Mode of Action, Resistance and Laboratory Diagnosis

Antibiotics toward Gram Positive Cocci: Mode of Action, Resistance and Laboratory Diagnosis PDF

Author: maysaa el sayed zaki

Publisher: GRIN Verlag

Published: 2013-08-20

Total Pages: 182

ISBN-13: 365648452X

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Document from the year 2013 in the subject Biology - Micro- and Molecular Biology, , language: English, abstract: Antimicrobial resistance remains, more than ever, a key issue for medical microbiology. The development of antibiotic resistance by bacteria is an evolutionary inevitability, a convincing demonstration of their ability to adapt to adverse environmental conditions. Some Gram-positive organisms are extremely adaptable and rapidly develop resistance, whereas others have not developed good strategies to overcome antibiotics. Staphylococci and enterococci, in particular are associated with clinically relevant resistance. The epithet of superbugs, if one can define these as bacterial pathogens resistant to almost all clinically available agents, can be truly applied to resistant strains of Gram-positive species, especially to methicillin-resistant Staphylococcus aureus (MRSA) and to glycopeptide- or vancomycinresistant enterococci (GRE or VRE).