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Principles of Cloning

Author: Jose Cibelli

Publisher: Academic Press

Published: 2013-09-24

Total Pages: 572

ISBN-13: 0123865425

Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning technique, including the first demonstration that cloning works in differentiated cells done by the Recipient of the 2012 Nobel Prize for Physiology or Medicine – Dr John Gurdon; the cloning of the first mammal from a somatic cell – Drs Keith Campbell and Ian Wilmut; the demonstration that cloning can reset the biological clock - Drs Michael West and Robert Lanza; the demonstration that a terminally differentiated cell can give rise to a whole new individual – Dr Rudolf Jaenisch and the cloning of the first transgenic bovine from a differentiated cell – Dr Jose Cibelli. The majority of the contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. First and most comprehensive book on animal cloning, 100% revised Describes an in-depth analysis of current limitations of the technology and research areas to explore Offers cloning applications on basic biology, agriculture, biotechnology, and medicine

Animal Cloning

Author: Shiv Sanjeevi

Publisher: Delve Publishing

Published: 2017-11

Total Pages: 0

ISBN-13: 9781773611877

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The creation of genetically identical organisms, referred to as cloning has propelled researchers to attempt to clone several organisms from microbes to plants to animals. The creation of "Dolly", the first cloned mammal, a sheep where an adult cell was used to produce an offspring instead of an embryo that develops into an organism ushered in a race to clone several other animals. The scope of animal cloning includes the production of genetically engineered organisms that have specific desired traits, the principles of molecular pharming where cloned animals produce therapeutics in their products, xenotransplantation, pharmacological testing, medical uses like study of diseases and potential cures, to name a few. Certain attempts are on to revive extinct animals. (Remember Jurassic Park?)This book covers principles and tools involved in animal cloning along with various animals that have been cloned and their potentials in biotechnology. The book shall also include various ethical issues associated with this field and summarize the work done in cloning. Threaders must note that these issues and regulations have been quoted verbatim so that the meaning conveyed does not change.

Scientific and Medical Aspects of Human Reproductive Cloning

Author: National Research Council

Publisher: National Academies Press

Published: 2002-06-17

Total Pages: 295

ISBN-13: 0309076374

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Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.

Cloning Wild Life

Author: Carrie Friese

Publisher: NYU Press

Published: 2013-09-02

Total Pages: 260

ISBN-13: 081472910X

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The natural world is marked by an ever-increasing loss of varied habitats, a growing number of species extinctions, and a full range of new kinds of dilemmas posed by global warming. At the same time, humans are also working to actively shape this natural world through contemporary bioscience and biotechnology. In Cloning Wild Life, Carrie Friese posits that cloned endangered animals in zoos sit at the apex of these two trends, as humans seek a scientific solution to environmental crisis. Often fraught with controversy, cloning technologies, Friese argues, significantly affect our conceptualizations of and engagements with wildlife and nature. By studying animals at different locations, Friese explores the human practices surrounding the cloning of endangered animals. She visits zoos—the San Diego Zoological Park, the Audubon Center in New Orleans, and the Zoological Society of London—to see cloning and related practices in action, as well as attending academic and medical conferences and interviewing scientists, conservationists, and zookeepers involved in cloning. Ultimately, she concludes that the act of recalibrating nature through science is what most disturbs us about cloning animals in captivity, revealing that debates over cloning become, in the end, a site of political struggle between different human groups. Moreover, Friese explores the implications of the social role that animals at the zoo play in the first place—how they are viewed, consumed, and used by humans for our own needs. A unique study uniting sociology and the study of science and technology, Cloning Wild Life demonstrates just how much bioscience reproduces and changes our ideas about the meaning of life itself.

Animal Cloning

Author: Joseph Panno

Publisher: Facts on File

Published: 2011

Total Pages: 0

ISBN-13: 9780816068470

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The New Biology is a 10-volume set that has evolved to accommodate new material and new areas of research, in keeping with the expansion of the biological disciplines and the development and application of research technologies in and out of the scientific laboratory. Since its publication several years ago, the set now includes four new volumes that focus on issues that cover the spectrum of human health, maintenance, and stability. Animal Cloning, Revised Edition is a compelling presentation of the questions, controversies, and motivations surrounding this extraordinary area of science. The book features an unbiased view of the complex debate surrounding cloning technology, especially with regard to therapeutic and reproductive cloning using stem cells harvested from human embryos. The ability to clone a mammal was the culmination of research in cell and developmental biology that goes back to the late 1800s. From the origin of the idea of cloning a mammal in 1898 to the reality of cloned animals in the 20th and 21st centuries to recent worldwide findings on the scientific and ethical aspects of cloning, this volume covers all facets of this unusual technology. The volume includes information on the "birth" of the cloned sheep Dolly commercialization of animal cloning current spectrum of clones ethical and legal issues of cloning history of animal cloning organ farming therapeutic cloning transgenic clones The book contains nearly 50 color photographs and line illustrations, a Resource Center of supporting materials in cell biology and biotechnology, a glossary, a list of print and Internet resources, and an index. The New Biology set is essential for middle and high school students, teachers, and general readers who wish to understand the latest information on this controversial area of scientific research. Book jacket.

Animal Transgenesis and Cloning

Author: Louis-Marie Houdebine

Publisher: Wiley-Blackwell

Published: 2003-04-02

Total Pages: 248

ISBN-13:

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Designed to be a concise, balanced introduction to this dynamic subject, covering key issues and current techniques currently used in animal transgenesis and cloning. Provides the essentials of the subject, from the molecular basis of gene structure and function to therapeutic gene cloning in humans. Social and ethical implications of this important area of research are also considered.

Cloning After Dolly

Author: Gregory E. Pence

Publisher: Rowman & Littlefield

Published: 2004

Total Pages: 240

ISBN-13: 9780742534087

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In a new book building on his classic Who's afraid of Human Cloning? Pence continues to advocate a reasoned view of cloning.

Forgotten Clones

Author: Nathan Crowe

Publisher: University of Pittsburgh Press

Published: 2021-12-07

Total Pages: 297

ISBN-13: 0822987686

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Long before scientists at the Roslin Institute in Scotland cloned Dolly the sheep in 1996, American embryologist and aspiring cancer researcher Robert Briggs successfully developed the technique of nuclear transplantation using frogs in 1952. Although the history of cloning is often associated with contemporary ethical controversies, Forgotten Clones revisits the influential work of scientists like Briggs, Thomas King, and Marie DiBerardino, before the possibility of human cloning and its ethical implications first registered as a concern in public consciousness, and when many thought the very idea of cloning was experimentally impossible. By focusing instead on new laboratory techniques and practices and their place in Anglo-American science and society in the mid-twentieth century, Nathan Crowe demonstrates how embryos constructed in the lab were only later reconstructed as ethical problems in the 1960s and 1970s with the emergence of what was then referred to as the Biological Revolution. His book illuminates the importance of the early history of cloning for the biosciences and their institutional, disciplinary, and intellectual contexts, as well as providing new insights into the changing cultural perceptions of the biological sciences after Second World War.

Human Cloning

Author: Kristi Lew

Publisher: The Rosen Publishing Group, Inc

Published: 2018-07-15

Total Pages: 66

ISBN-13: 1508180369

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As a genre, science fiction has the unique ability to inspire curiosity and deepen the understanding of issues that are facing STEM fields. One of those issues is the possibility of human cloning. This book examines how human cloning has been depicted in science fiction, the development of existing cloning technology, how scientists have used these techniques in the past, and their potential application for the future. Fascinated readers will explore topics such as somatic cell nuclear transfer (SCNT), animal cloning, and the ethical considerations surrounding therapeutic and reproductive cloning in humans.

Safety of Genetically Engineered Foods

Author: National Research Council

Publisher: National Academies Press

Published: 2004-07-08

Total Pages: 254

ISBN-13: 0309166152

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Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.