Etiology of Parkinson's Disease

Etiology of Parkinson's Disease PDF

Author: Jonas H. Ellenberg

Publisher: CRC Press

Published: 1995-03-01

Total Pages: 600

ISBN-13: 9780824788230

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This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders PDF

Author: Michael J. Zigmond

Publisher: Elsevier

Published: 2014-12-03

Total Pages: 823

ISBN-13: 0123982804

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Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Genetics, Neurology, Behavior, and Diet in Parkinson's Disease

Genetics, Neurology, Behavior, and Diet in Parkinson's Disease PDF

Author: Colin R Martin

Publisher: Academic Press

Published: 2020-08-13

Total Pages: 764

ISBN-13: 0128159510

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Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease

Alpha-Synuclein

Alpha-Synuclein PDF

Author: Mark Polizzi

Publisher:

Published: 2013

Total Pages: 86

ISBN-13: 9781629484945

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Book Description: Alpha-synuclein is a synuclein protein of unknown function primarily found in neural tissue, making up as much as 1% of all proteins in the cytosol. It is predominantly expressed in the neocortex, hippocampus, substantia nigra, thalamus, and cerebellum. In this book, the authors discuss the functional mechanisms, structure and role in Parkinson's disease of alpha-synuclein. Topics include -synuclein accumulation in Parkinson's disease and multiple system atrophy; -synuclein metabolism and aggregation in the pathogenesis of Parkinson's disease; and the potential role of -synuclein dysregulation in Parkinson's disease pathology.

Alpha-synuclein

Alpha-synuclein PDF

Author: Howard C. Kanowitz

Publisher: Nova Science Pub Incorporated

Published: 2013-01-01

Total Pages: 61

ISBN-13: 9781629484938

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Alpha-synuclein is a synuclein protein of unknown function primarily found in neural tissue, making up as much as 1% of all proteins in the cytosol. It is predominantly expressed in the neocortex, hippocampus, substantia nigra, thalamus, and cerebellum. In this book, the authors discuss the functional mechanisms, structure and role in Parkinson's disease of alpha-synuclein. Topics include α-synuclein accumulation in Parkinsons disease and multiple system atrophy; α-synuclein metabolism and aggregation in the pathogenesis of Parkinsons disease; and the potential role of α-synuclein dysregulation in Parkinsons disease pathology.

Brain Transcriptome

Brain Transcriptome PDF

Author:

Publisher: Academic Press

Published: 2014-08-27

Total Pages: 365

ISBN-13: 0128013192

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Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume, concentrates on the brain transcriptome. Brings together cutting-edge research on the brain transcriptome

Pathology, Prevention and Therapeutics of Neurodegenerative Disease

Pathology, Prevention and Therapeutics of Neurodegenerative Disease PDF

Author: Sarika Singh

Publisher: Springer

Published: 2018-09-24

Total Pages: 301

ISBN-13: 9811309442

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This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases