-PDF Download- Alpha Fetoprotein And Its Receptor In Fixing The Cancer Brakes EBOOK

Alpha-fetoprotein and Its Receptor in Fixing the Cancer Brakes

Author: Vladimir N. Pak

Publisher: Cambridge Scholars Publishing

Published: 2021-03-25

Total Pages: 209

ISBN-13: 1527567729

This book examines the crucial role of a unique alpha-fetoprotein (AFP) in the treatment of cancer. AFP can deliver toxins through specific receptors re-expressed in the majority of cancer cells, serving as a targeted chemotherapy. More importantly, AFP+toxin harnesses the patient’s immune system in order to attack cancer. Depleting the regulatory top monocyte-derived suppressor cells (MDSCs) activates both the innate and adaptive immune responses. The thoroughly chosen toxins switch on apoptosis in MDSCs, restore the broken one in cancer cells, and destroy them naturally without any harmful by-products. Injections with AFP+toxin preparations have shown promising results in animals and the treatment of cancer patients. In addition to this breakthrough, the book also discusses the peroral administration of porcine AFP non-covalent complexes with selected toxins in patients with metastases. It will appeal to science researchers, clinicians, and medical students, as well as the more general reader.

Alpha-Fetoprotein

Author: Nisha Lakhi

Publisher:

Published: 2016-06-01

Total Pages:

ISBN-13: 9781634849005

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Cancer Rehabilitation 2E

Author: Michael D. Stubblefield, MD

Publisher: Springer Publishing Company

Published: 2018-09-28

Total Pages: 1200

ISBN-13: 0826121640

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Praise for the previous edition: “This book is a milestone and must-have for anyone involved in the care of those with cancer." --American Journal of Physical Medicine and Rehabilitation “This reference provides a comprehensive, pragmatic approach for physical medicine physicians; speech, occupational, and physical therapists; and nurses with cancer survivor responsibilities...[A]ny cancer program with significant rehabilitation services will find this a useful addition to its library.” --JAMA (Journal of the American Medical Association) This completely revised second edition of the gold-standard reference on cancer rehabilitation provides a state-of-the-art overview of the principles of cancer care and best practices for restoring function and quality of life to cancer survivors. Authored by some of the world’s leading cancer rehabilitation experts and oncology specialists, the book opens with primer-level discussions of the various cancer types and their assessment and management, including potential complications, as a foundation for providing safe and effective rehabilitation. Subsequent sections thoroughly explore the identification, evaluation, and treatment of specific impairments and disabilities that result from cancer and the treatment of cancer. Designed to serve the needs of the entire medical team, this singular resource is intended for any clinician working with cancer survivors to improve function and quality of life. With several new chapters on topics such as inpatient cancer rehabilitation, pediatric oncology, research issues, and barriers to accessing cancer rehabilitation and building a cancer rehabilitation program, the book keeps pace with recent advances in the growing field of cancer rehabilitation. This new edition features updates throughout and expansions to major topics, including imaging in cancer and key disorders such as aromatase inhibitor-induced arthralgias. Presenting the most current medical, clinical, and rehabilitation intelligence, this is a mandatory reference for anyone in the field. Key Features: New edition of the only contemporary comprehensive text covering the field of cancer rehabilitation Revised and updated to reflect current knowledge, practice, and emerging topics Covers essential aspects of oncology and medical complications of cancer to inform rehabilitation decisions and strategies Provides state-of-the-art reviews on all major topics in cancer rehabilitation, including pain assessment and management, neuromuscular and musculoskeletal dysfunction, neurologic, and general rehabilitation issues 13 new chapters and expanded coverage of signature areas Key points are provided for each chapter to reinforce learning

Alcohol and Cancer

Author: Vasilis Vasiliou

Publisher: Springer

Published: 2018-10-26

Total Pages: 271

ISBN-13: 3319987887

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Following the Third Alcohol and Cancer Conference, this volume compiles the most up-to-date research on the role of alcohol consumption in carcinogenesis, from epidemiology to pathology metabolism and stem cells. More specifically, it delves into the effects of alcohol consumption and thyroid cancer, CD133+ progenitor cells, carcinogenic iron accumulation, developmental morphogens, and cancer-inducing epigenetic changes. Alcohol and Cancer: Proceedings of the Third International Conference is a timely update to Biological Basis of Alcohol-Induced Cancer, which followed the Second Alcohol and Cancer Conference, compiling cutting-edge research from graduate students, young scientists, and researchers. It is ideal for graduate students and researchers in oncology, hepatology, epigenetics, and alcohol consumption.

Immunotherapy of Hepatocellular Carcinoma

Author: Tim F. Greten

Publisher: Springer

Published: 2018-08-22

Total Pages: 0

ISBN-13: 9783319879116

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In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

Cancer Vaccines and Immunotherapy

Author: Peter L. Stern

Publisher: Cambridge University Press

Published: 2000-08-17

Total Pages: 304

ISBN-13: 9780521622639

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Rapid progress in the definition of tumor antigens, and improved immunization methods, bring effective cancer vaccines within reach. In this wide-ranging survey, leading clinicians and scientists review therapeutic cancer vaccine strategies against a variety of diseases and molecular targets. Intended for an interdisciplinary readership, their contributions cover the rationale, development, and implementation of vaccines in human cancer treatment, with specific reference to cancer of the cervix, breast, colon, bladder, and prostate, and to melanoma and lymphoma. They review target identification, delivery vectors and clinical trial design. The book begins and ends with lucid overviews from the editors, that discuss the most recent developments.

Gaseous Molecular Ions

Author: Eugen Illenberger

Publisher: Springer Science & Business Media

Published: 1992-05-26

Total Pages: 944

ISBN-13: 9783798508705

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Most of the matter in our solar system, and, probably, within the whole universe, exists in the form of ionized particles. On the other hand, in our natural environ ment, gaseous matter generally consists of neutral atoms and molecules. Only under certain conditions, such as within the path oflightning or in several technical devices (e. g. gas discharges, rocket engines, etc. ) will some of the atoms and molecules be ionized. It is also believed that the chemistry of the earth's troposphere predomi nantly proceeds via reactions between neutral particles. (The complex system of atmospheric chemistry will be treated in one of the forthcoming volumes to this series. ) Why, then, are ions considered so important that hundreds oflaboratories all over the world (including some of the most prestigious) are involved in research pro grams on ions, covering many different facets, from biochemistry to physics? One may obtain as many different answers as there are research groups busy in this field. There is, however, one simple, common feature which makes it attractive to work with ions: since they carry one or more net elementary charges, they can easily be gui ded, focused or separated by appropriate electric and magnetic fields, and, last but not least, they can easily be detected. Apart from these advantages, which are welcome and appreciated by the researcher, the study of molecular ions can provide insight into very fundamental aspects of the general behavior of molecules.

Textbook of Gastrointestinal Oncology

Author: Suayib Yalcin

Publisher: Springer Nature

Published: 2019-09-05

Total Pages: 716

ISBN-13: 3030188906

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This textbook discusses core principles and practices in gastrointestinal oncology and covers a wide range of practice areas such as pathology and radiologic images, epidemiology, genetics, staging, multidisciplinary management of specific gastrointestinal cancer, and pathology for each primary tumor site. The comprehensive coverage makes Textbook of Gastrointestinal Oncology a useful resource for the practitioner wishing to gain a greater understanding of the principles of managing malignant gastrointestinal disease, as well as medical oncology fellows, surgeons, radiation oncologists, gastroenterologists and fellows, and residents.

Innate

Author: Kevin J. Mitchell

Publisher: Princeton University Press

Published: 2020-03-31

Total Pages: 305

ISBN-13: 0691204152

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"What makes you the way you are--and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired--differences that impact all aspects of our psychology--and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are."--Provided by the publisher.

Pediatric Board Study Guide

Author: Osama Naga

Publisher: Springer

Published: 2015-03-27

Total Pages: 611

ISBN-13: 3319101153

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Covers the most frequently asked and tested points on the pediatric board exam. Each chapter offers a quick review of specific diseases and conditions clinicians need to know during the patient encounter. Easy-to-use and comprehensive, clinicians will find this guide to be the ideal final resource needed before taking the pediatric board exam.