Alcohol and the Nervous System

Alcohol and the Nervous System PDF

Author: Edith V. Sullivan

Publisher: Elsevier

Published: 2014-10-08

Total Pages: 703

ISBN-13: 0444626220

DOWNLOAD EBOOK →

Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

The Effects of Drug Abuse on the Human Nervous System

The Effects of Drug Abuse on the Human Nervous System PDF

Author: Bertha Madras

Publisher: Elsevier

Published: 2013-11-15

Total Pages: 625

ISBN-13: 0124186858

DOWNLOAD EBOOK →

Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. A comprehensive reference on the effects of drug addiction on the human nervous system Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs Includes foundational science chapters on the biology of addiction Details challenges in diagnosis and treatment options

Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism

Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism PDF

Author: Aparajita Dey

Publisher: Springer Science & Business Media

Published: 2013-02-12

Total Pages: 269

ISBN-13: 9400758812

DOWNLOAD EBOOK →

The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1) which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic liver cirrhosis, inhibition of bone repair, cross-tolerance in smokers and people treated with nicotine, disorders of central nervous system, changes in metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Hence, CYP2E1 emerges as a new and potent player in aggravating injury and furthering disease complications.

Alcohol and the Brain

Alcohol and the Brain PDF

Author:

Publisher: DIANE Publishing

Published: 1993

Total Pages: 90

ISBN-13: 0788100327

DOWNLOAD EBOOK →

Covers: liver-brain relations; sever brain dysfunction; advances in neurochemistry; cognitive-processing deficits; alcohol reinforcement, and much more. Illustrated.

Caffeine in Food and Dietary Supplements

Caffeine in Food and Dietary Supplements PDF

Author: Leslie A. Pray

Publisher:

Published: 2014

Total Pages: 0

ISBN-13: 9780309297493

DOWNLOAD EBOOK →

Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.

The Biology of Alcoholism

The Biology of Alcoholism PDF

Author: Benjamin Kissin

Publisher: Springer

Published: 1972-02

Total Pages: 594

ISBN-13:

DOWNLOAD EBOOK →

Covers neurophysioligcal and psychological effects of alcohol on man. Includes extensive bibliographies covering the literature from 1920 through 1970

Development of the Central Nervous System

Development of the Central Nervous System PDF

Author: Michael W. Miller

Publisher: Wiley-Liss

Published: 1992

Total Pages: 424

ISBN-13:

DOWNLOAD EBOOK →

Disseminates information pertaining to the normal and abnormal processes involved during the development of the central nervous system. The toxic effects of alcohol or opiate usage on development are explored by examining the clinical manifestations that appear in the children of substance-abusing mothers. Detailed coverage includes individual ontogenetic and developmental processes such as neural chemical differentiation, cell proliferation and migration.