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Author: United States Senate
Publisher:
Published: 2019-11-30
Total Pages: 66
ISBN-13: 9781713310167
DOWNLOAD EBOOK →Advanced manufacturing and biotechnology: field hearing before the Committee on Commerce, Science, and Transportation, United States Senate, One Hundred Eighth Congress, first session, April 14, 2003.
Author: United States. Congress
Publisher: Createspace Independent Publishing Platform
Published: 2018-02-09
Total Pages: 64
ISBN-13: 9781985235595
DOWNLOAD EBOOK →Advanced manufacturing and biotechnology : field hearing before the Committee on Commerce, Science, and Transportation, United States Senate, One Hundred Eighth Congress, first session, April 14, 2003.
Author: United States. Congress. Senate. Committee on Commerce, Science, and Transportation
Publisher:
Published: 2005
Total Pages: 64
ISBN-13:
DOWNLOAD EBOOK →Author: National Research Council
Publisher: National Academies Press
Published: 2015-06-29
Total Pages: 167
ISBN-13: 0309316553
DOWNLOAD EBOOK →The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.
Author: Christoph Wittmann
Publisher: John Wiley & Sons
Published: 2017-03-06
Total Pages: 642
ISBN-13: 3527341811
DOWNLOAD EBOOK →The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.
Author: Cenk Undey
Publisher: CRC Press
Published: 2011-12-07
Total Pages: 330
ISBN-13: 1439829454
DOWNLOAD EBOOK →As with all of pharmaceutical production, the regulatory environment for the production of therapeutics has been changing as a direct result of the US FDA-initiated Quality by Design (QbD) guidelines and corresponding activities of the International Committee for Harmonization (ICH). Given the rapid growth in the biopharmaceutical area and the complexity of the molecules, the optimum use of which are still being developed, there is a great need for flexible and proactive teams in order to satisfy the regulatory requirements during process development. Process Analytical Technologies (PAT) applied in biopharmaceutical process development and manufacturing have received significant attention in recent years as an enabler to the QbD paradigm. PAT Applied in Biopharmaceutical Process Development and Manufacturing covers technological advances in measurement sciences, data acquisition, monitoring, and control. Technical leaders present real-life case studies in areas including measuring and monitoring raw materials, cell culture, purification, and cleaning and lyophilization processes via advanced PAT. They also explore how data are collected and analyzed using advanced analytical techniques such as multivariate data analysis, monitoring, and control in real-time. Invaluable for experienced practitioners in PAT in biopharmaceuticals, this book is an excellent reference guide for regulatory officials and a vital training aid for students who need to learn the state of the art in this interdisciplinary and exciting area.
Author: Stephen E. Saddow
Publisher: Elsevier
Published: 2011-11-14
Total Pages: 496
ISBN-13: 0123859077
DOWNLOAD EBOOK →Silicon Carbide (SiC) is a wide-band-gap semiconductor biocompatible material that has the potential to advance advanced biomedical applications. SiC devices offer higher power densities and lower energy losses, enabling lighter, more compact and higher efficiency products for biocompatible and long-term in vivo applications ranging from heart stent coatings and bone implant scaffolds to neurological implants and sensors. The main problem facing the medical community today is the lack of biocompatible materials that are also capable of electronic operation. Such devices are currently implemented using silicon technology, which either has to be hermetically sealed so it cannot interact with the body or the material is only stable in vivo for short periods of time. For long term use (permanent implanted devices such as glucose sensors, brain-machine-interface devices, smart bone and organ implants) a more robust material that the body does not recognize and reject as a foreign (i.e., not organic) material is needed. Silicon Carbide has been proven to be just such a material and will open up a whole new host of fields by allowing the development of advanced biomedical devices never before possible for long-term use in vivo. This book not only provides the materials and biomedical engineering communities with a seminal reference book on SiC that they can use to further develop the technology, it also provides a technology resource for medical doctors and practitioners who are hungry to identify and implement advanced engineering solutions to their everyday medical problems that currently lack long term, cost effective solutions. Discusses Silicon Carbide biomedical materials and technology in terms of their properties, processing, characterization, and application, in one book, from leading professionals and scientists Critical assesses existing literature, patents and FDA approvals for clinical trials, enabling the rapid assimilation of important data from the current disparate sources and promoting the transition from technology research and development to clinical trials Explores long-term use and applications in vivo in devices and applications with advanced sensing and semiconducting properties, pointing to new product devekipment particularly within brain trauma, bone implants, sub-cutaneous sensors and advanced kidney dialysis devices
Author: The National Science and Technology Coun
Publisher: Createspace Independent Publishing Platform
Published: 2016
Total Pages: 57
ISBN-13: 9781544064901
DOWNLOAD EBOOK →Photo's removed due to copyright restrictions. Advanced manufacturing drives long-term economic prosperity and growth, and supports the missions of the Federal agencies participating in the NSTC Subcommittee for Advanced Manufacturing (SAM). A foundation of priority technology areas is needed to secure U.S. competitiveness in this sector, from which collaborations between government, industry, and academia may be built. This document captures technology areas in advanced manufacturing that are current priorities for the Federal Government, and are strong candidates for focused Federal investment and public-private collaboration. Emerging technology areas include advanced materials manufacturing, engineering biology to advance biomanufacturing, biomanufacturing for regenerative medicine, advanced bioproducts manufacturing, and continuous manufacturing of pharmaceuticals. In addition, the Federal Government has already announced a number of advanced manufacturing technology areas that are either the focus of substantial existing investments or that may be the subject of future programming. These existing technology areas similarly require support across the development pipeline to fully leverage current research and development investments and infrastructure. Finally, Federal education and workforce training programs for manufacturing, which encourage strong industry involvement to ensure that today's curricula meet tomorrow's workforce needs, are highlighted.
Author: Atul Babbar
Publisher: CRC Press
Published: 2022-07-29
Total Pages: 266
ISBN-13: 1000622959
DOWNLOAD EBOOK →This book covers innovative breakthroughs in additive manufacturing processes used for biomedical engineering. More and more, 3D printing is selected over traditional manufacturing processes, especially for complex designs, because of the many advantages such as fewer restrictions, better production cost savings, higher quality control, and accuracy. Current challenges and opportunities regarding material, design, cost savings, and efficiency are covered along with an outline of the most recent fabrication methods used for converting biomaterials into integrated structures that can fit best in anatomy while still obtaining the necessary architecture, mechanical reliability, biocompatibility, and anti-bacterial characteristics needed. Additional chapters will also focus on selected areas of applications such as bionics, affordable prostheses, implants, medical devices, rapid tooling, and drug delivery. Additive Manufacturing Processes in Biomedical Engineering: Advanced Fabrication Methods and Rapid Tooling Techniques acts as a first-hand reference for commercial manufacturing organizations which are mimicking tissue organs by using additive manufacturing techniques. By capturing the current trends of today’s manufacturing practices this book becomes a one-stop resource for manufacturing professionals, engineers in related disciplines, and academic researchers.
Author: Alexandru Mihai Grumezescu
Publisher: Academic Press
Published: 2018-02-03
Total Pages: 508
ISBN-13: 0128114959
DOWNLOAD EBOOK →Advances in Biotechnology for Food Industry, Volume Fourteen in the Handbook of Food Bioengineering series, provides recent insight into how biotechnology impacts the global food industry and describes how food needs are diverse, requiring the development of innovative biotechnological processes to ensure efficient food production worldwide. Many approaches were developed over the last 10 years to allow faster, easier production of widely used foods, food components and therapeutic food ingredients. This volume shows how biotechnological processes increase production and quality of food products, including the development of anti-biofilm materials to decrease microbial colonization in bioreactors and food processing facilities. Presents basic to advanced technological applications in food biotechnology Includes various scientific techniques used to produce specific desired traits in plants, animals and microorganisms Provides scientific advances in food processing and their impact on the environment, human health and food safety Discusses the development of controlled co-cultivations for reproducible results in fermentation processes in food biotechnology
