Bioactive Materials for Disease Diagnosis and Therapy

Bioactive Materials for Disease Diagnosis and Therapy PDF

Author: Dan Shao

Publisher: Frontiers Media SA

Published: 2024-04-16

Total Pages: 249

ISBN-13: 2832547885

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With their advantages of controlled delivery and modular flexibility, biomaterials have fundamentally revolutionized disease diagnosis and therapy. Bioactive nanomaterials are not simple miniaturizations of macroscopic materials. They exhibit unique and intrinsic bioactivities as they readily acquire a precise structure upon interaction with the biological environment. Nowadays, bioactive materials offer great potential in eliciting specific responses and regulations of living tissues for diagnostics, therapeutics, and regenerative medicine. We are optimistic that the increasing innovations and advances in bioactive and biomimetic materials with sophisticated bioactivities and controllable responsiveness will make an important contribution to the next generation of biomaterials and biomedical engineering.

Advanced Drug Delivery Systems in the Management of Cancer

Advanced Drug Delivery Systems in the Management of Cancer PDF

Author: Kamal Dua

Publisher: Elsevier

Published: 2021-06-24

Total Pages: 572

ISBN-13: 0323900798

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Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Advanced Approaches in the Diagnosis and Treatment of Diabetes Mellitus and Secondary Complications

Advanced Approaches in the Diagnosis and Treatment of Diabetes Mellitus and Secondary Complications PDF

Author: Pranav Kumar Prabhakar

Publisher: Frontiers Media SA

Published: 2023-10-23

Total Pages: 509

ISBN-13: 2832536328

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As we know diabetes mellitus is the most common metabolic endocrine disorder. According to the WHO and American Diabetes Mellitus, diabetes mellitus is the 3rd leading cause of death if we were to include all secondary complications. However without including secondary complications, it is 7th place in mortality and morbidity. The point to be considered in the case of diabetes mellitus is the secondary complications caused in this condition. Almost all organs affected by diabetes and results in a potentially worse condition. The major secondary complications are neuropathy, nephropathy, retinopathy, and diabetes foot microvascular and macrovascular complications. The long term complications grow slowly in the case of diabetes. As the time living with diabetes becomes longer, controlled glucose levels will be more difficult to achieve, meaning there there will be more long term complications. The aim of the current Research Topic on the secondary complications of diabetes and their management is to publish good quality research articles as well as reviews, which should address the management of diabetes, abnormalities of secondary complications and other disease involved in diabetes. Potential Topics includes but not restricted to: • Secondary complications of diabetes mellitus • Microvascular and macrovascular complications • The role of oxidative stress in the diabetes burden • New insights in glycemic control • New strategies/ approaches to manage secondary complications such as Stearoyl CoA dismutase, Acetyl CoA Carboxylase, Adiponectin/ Adipocyte complement-related protein 30, Hormone Sensitive Lipase (HSL) Inhibitors • Recent development in the therapeutic approaches for glucose management such as Protein tyrosine phosphatase-1B (PTP1B) inhibitors, Glycogen synthase kinase-3 (GSK3) inhibitors, β3- Adrenergic receptor agonist, Retinoid X receptor, PPARα agonist, AMP activated protein kinase • Development of new target as a target for antihyperglycemic drug designing

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases PDF

Author: Mahendra Rai

Publisher: Academic Press

Published: 2015-05-23

Total Pages: 341

ISBN-13: 0128014717

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Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections

Recent Progress in Antimicrobial Nanomaterials

Recent Progress in Antimicrobial Nanomaterials PDF

Author: Ana María Díez-Pascual

Publisher: MDPI

Published: 2021-01-20

Total Pages: 228

ISBN-13: 3039439596

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Based on a fundamental understanding of the interaction between bacteria and nanomaterials, this book highlights the latest research on the antimicrobial properties of nanomaterials and provides an invaluable blueprint for improving the antimicrobial performance of devices and products. This book introduces the reader to the progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed. The content provides insight into the ongoing research, current trends, and technical challenges in this rapidly progressing field. Therefore, this book is highly suitable for materials scientists, engineers, biologists, and technologists.

Selected Health Conditions and Likelihood of Improvement with Treatment

Selected Health Conditions and Likelihood of Improvement with Treatment PDF

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2020-07-12

Total Pages: 319

ISBN-13: 0309670950

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The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.

Nanoparticles in Medicine

Nanoparticles in Medicine PDF

Author: Ashutosh Kumar Shukla

Publisher: Springer Nature

Published: 2019-08-31

Total Pages: 220

ISBN-13: 9811389543

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This book describes the medical applications of inorganic nanoparticles. Nanomedicine is a relatively advanced field, which enhances the treatment of various diseases, offering new options for overcoming the problems associated with the use of conventional medicines. Discussing the toxicological and safety aspects associated with medical applications of nanoparticles, the book presents the latest research on topics such as emerging nanomaterials for cancer therapy, applications of nanoparticles in dentistry, and fluoride nanoparticles for biomedical applications, and also includes chapters on the use of nanoparticles such as silver and gold. /div

Advanced Healthcare Materials

Advanced Healthcare Materials PDF

Author: Ashutosh Tiwari

Publisher: John Wiley & Sons

Published: 2014-05-09

Total Pages: 421

ISBN-13: 1118773683

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Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents PDF

Author: Manju Rawat Singh

Publisher: Academic Press

Published: 2020-04-07

Total Pages: 657

ISBN-13: 0128199180

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Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive medicine transporters can cure many disorders by both spatial and transitory approaches and have various justifications in medicinal potential. This book presents information on the utility of natural, plant, animal and bioengineered bioactive materials. It is a fundamental source of information and data for pharmacognosists, pharmaceutical analysts, drug transport scientists and pharmacologists working in bioactive medications. Advances information on various bioactive based medications, their sources, clinical consequences and transport strategies Illustrates diverse transport systems for bioactives and derivatives, novel techniques for formulations, targeting strategies and fundamental qualities of developed bioactive carriers, and their safety concerns and standardization Discusses distinctive transport systems, stability, upgraded dissolvability, and enhanced bioavailability of bioactives