A Primer of Population Genetics and Genomics

A Primer of Population Genetics and Genomics PDF

Author: Daniel L. Hartl

Publisher: Oxford University Press

Published: 2020-06-18

Total Pages: 272

ISBN-13: 0192607049

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A Primer of Population Genetics and Genomics has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics. Recent textbooks have tended to focus on such specialized topics as the coalescent, molecular evolution, human population genetics, or genomics. This primer bucks that trend by encouraging a broader familiarity with, and understanding of, population genetics and genomics as a whole. The overview ranges from mating systems through the causes of evolution, molecular population genetics, and the genomics of complex traits. Interwoven are discussions of ancient DNA, gene drive, landscape genetics, identifying risk factors for complex diseases, the genomics of adaptation and speciation, and other active areas of current research. The principles are illuminated by numerous examples from a wide variety of animals, plants, microbes, and human populations. The approach also emphasizes learning by doing, which in this case means solving numerical or conceptual problems. The rationale behind this is that the use of concepts in problem-solving lead to deeper understanding and longer knowledge retention. This accessible, introductory textbook is aimed principally at students of various levels and abilities (from senior undergraduate to postgraduate) as well as practising scientists in the fields of population genetics, ecology, evolutionary biology, computational biology, bioinformatics, biostatistics, physics, and mathematics.

A Primer of Population Genetics

A Primer of Population Genetics PDF

Author: Daniel L. Hartl

Publisher: Sinauer Associates, Incorporated

Published: 1988

Total Pages: 326

ISBN-13: 9780878933013

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The use of molecular methods to study genetic polymorphisms has made a familiarity with population genetics essential for any biologist whose work is at the population level. A Primer of Population Genetics, Third Edition provides a concise but comprehensive introduction to population genetics. The four chapters of the book address genetic variation, the causes of evolution, molecular population genetics, and the genetic architecture of complex traits. Chapter-end problems reinforce ideas and, while there are some equations, the emphasis is on explanation rather than derivation.

A Primer of Molecular Population Genetics

A Primer of Molecular Population Genetics PDF

Author: Asher D. Cutter

Publisher: Oxford University Press, USA

Published: 2019

Total Pages: 266

ISBN-13: 0198838948

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What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.

A Primer of Population Genetics and Genomics

A Primer of Population Genetics and Genomics PDF

Author: Daniel L. Hartl

Publisher:

Published: 2020

Total Pages:

ISBN-13: 9780191895074

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This accessible primer has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.

A Primer of Molecular Population Genetics

A Primer of Molecular Population Genetics PDF

Author: Asher D. Cutter

Publisher: Oxford University Press

Published: 2019-06-06

Total Pages: 266

ISBN-13: 0192575546

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What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.

A Primer of Ecological Genetics

A Primer of Ecological Genetics PDF

Author: Jeffrey K. Conner

Publisher: Sinauer Associates Incorporated

Published: 2004-01

Total Pages: 304

ISBN-13: 9780878932023

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This book covers basic concepts in population and quantitative genetics, including measuring selection on phenotypic traits. The emphasis is on material applicable to field studies of evolution focusing on ecologically important traits. Topics addressed are critical for training students in ecology, evolution, conservation biology, agriculture, forestry, and wildlife management. Many texts in this field are too complex and mathematical to allow the average beginning student to readily grasp the key concepts. A Primer of Ecological Genetics, in contrast, employs mathematics and statistics-fully explained, but at a less advanced level-as tools to improve understanding of biological principles. The main goal is to enable students to understand the concepts well enough that they can gain entry into the primary literature. Integration of the different chapters of the book shows students how diverse concepts relate to each other.

Molecular Population Genetics

Molecular Population Genetics PDF

Author: Matthew William Hahn

Publisher: Sinauer Associates, Incorporated

Published: 2018

Total Pages: 334

ISBN-13: 9780878939657

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Published by Sinauer Associates, an imprint of Oxford University Press. Provides descriptions of the methods and tools used in molecular population genetics, which has combined advances in molecular biology and genomics with mathematical and empirical findings to uncover the history of natural selection and demographic shifts in many organisms.

Population Genetics

Population Genetics PDF

Author: Matthew B. Hamilton

Publisher: John Wiley & Sons

Published: 2011-09-23

Total Pages: 658

ISBN-13: 1444362453

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This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.

Conservation and the Genomics of Populations

Conservation and the Genomics of Populations PDF

Author: Fred W. Allendorf

Publisher: Oxford University Press

Published: 2022

Total Pages: 785

ISBN-13: 0198856563

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The relentless loss of biodiversity is among the greatest problems facing the world today. The third edition of this established textbook provides an updated and comprehensive overview of the essential background, concepts, and tools required to understand how genetics can be used to conservespecies, reduce threat of extinction, and manage species of ecological or commercial importance. This edition is thoroughly revised to reflect the major contribution of genomics to conservation of populations and species. It includes two new chapters: "Genetic Monitoring" and a final "ConservationGenetics in Practice" chapter that addresses the role of science and policy in conservation genetics.New genomic techniques and statistical analyses are crucial tools for the conservation geneticist. This accessible and authoritative textbook provides an essential toolkit grounded in population genetics theory, coupled with basic and applied research examples from plants, animals, and microbes. Thebook examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, evolutionary response to anthropogenic change, and applications in conservation and management.Conservation and the Genomics of Populations helps demystify genetics and genomics for conservation practitioners and early career scientists, so that population genetic theory and new genomic data can help raise the bar in conserving biodiversity in the most critical 20 year period in the historyof life on Earth. It is aimed at a global market of applied population geneticists, conservation practitioners, and natural resource managers working for wildlife and habitat management agencies. It will be of particular relevance and use to upper undergraduate and graduate students taking coursesin conservation biology, conservation genetics, and wildlife management.