A History of the Life Sciences, Revised and Expanded

A History of the Life Sciences, Revised and Expanded PDF

Author: Lois N. Magner

Publisher: CRC Press

Published: 2002-08-13

Total Pages: 522

ISBN-13: 9780203911006

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A clear and concise survey of the major themes and theories embedded in the history of life science, this book covers the development and significance of scientific methodologies, the relationship between science and society, and the diverse ideologies and current paradigms affecting the evolution and progression of biological studies. The author d

A History of the Life Sciences

A History of the Life Sciences PDF

Author: Lois N. Magner

Publisher: Marcel Dekker

Published: 1994

Total Pages: 520

ISBN-13:

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A clear and concise survey of the major themes and theories embedded in the history of life science, this book covers the development and significance of scientific methodologies, the relationship between science and society, and the diverse ideologies and current paradigms affecting the evolution and progression of biological studies. The author discusses cell theory, embryology, physiology, microbiology, evolution, genetics, and molecular biology; the Human Genome Project; and genomics and proteomics. Covering the philosophies of ancient civilizations to modern advances in genomics and molecular biology, the book is a unique and comprehensive resource.

Who Wrote the Book of Life?

Who Wrote the Book of Life? PDF

Author: Lily E. Kay

Publisher: Stanford University Press

Published: 2000

Total Pages: 476

ISBN-13: 9780804734172

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This is a detailed history of one of the most important and dramatic episodes in modern science, recounted from the novel vantage point of the dawn of the information age and its impact on representations of nature, heredity, and society. Drawing on archives, published sources, and interviews, the author situates work on the genetic code (1953-70) within the history of life science, the rise of communication technosciences (cybernetics, information theory, and computers), the intersection of molecular biology with cryptanalysis and linguistics, and the social history of postwar Europe and the United States. Kay draws out the historical specificity in the process by which the central biological problem of DNA-based protein synthesis came to be metaphorically represented as an information code and a writing technology—and consequently as a “book of life.” This molecular writing and reading is part of the cultural production of the Nuclear Age, its power amplified by the centuries-old theistic resonance of the “book of life” metaphor. Yet, as the author points out, these are just metaphors: analogies, not ontologies. Necessary and productive as they have been, they have their epistemological limitations. Deploying analyses of language, cryptology, and information theory, the author persuasively argues that, technically speaking, the genetic code is not a code, DNA is not a language, and the genome is not an information system (objections voiced by experts as early as the 1950s). Thus her historical reconstruction and analyses also serve as a critique of the new genomic biopower. Genomic textuality has become a fact of life, a metaphor literalized, she claims, as human genome projects promise new levels of control over life through the meta-level of information: control of the word (the DNA sequences) and its editing and rewriting. But the author shows how the humbling limits of these scriptural metaphors also pose a challenge to the textual and material mastery of the genomic “book of life.”

Data Analysis for the Life Sciences with R

Data Analysis for the Life Sciences with R PDF

Author: Rafael A. Irizarry

Publisher: CRC Press

Published: 2016-10-04

Total Pages: 461

ISBN-13: 1498775861

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This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

Ideology and Rationality in the History of the Life Sciences

Ideology and Rationality in the History of the Life Sciences PDF

Author: Georges Canguilhem

Publisher: Cambridge, Mass. : MIT Press

Published: 1988

Total Pages: 184

ISBN-13:

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Throughout his long career Canguilhem has been concerned with the way in which ideas originate and become transformed in scientific discourse, and with the role played by ideological factors in determining the direction if not the results of scientific work. This book collects his published essays of the 1970s.

Books and the Sciences in History

Books and the Sciences in History PDF

Author: Marina Frasca-Spada

Publisher: Cambridge University Press

Published: 2000-11-02

Total Pages: 460

ISBN-13: 9780521659390

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This book, published in 2000, examines the intersection between science and books from early medieval times to the nineteenth century.

Life Atomic

Life Atomic PDF

Author: Angela N. H. Creager

Publisher: University of Chicago Press

Published: 2013-10-02

Total Pages: 506

ISBN-13: 022601794X

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After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. Even as the atomic bomb became the focus of Cold War anxiety, radioisotopes represented the government’s efforts to harness the power of the atom for peace—advancing medicine, domestic energy, and foreign relations. In Life Atomic, Angela N. H. Creager tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology. Government-produced radioisotopes provided physicians with new tools for diagnosis and therapy, specifically cancer therapy, and enabled biologists to trace molecular transformations. Yet the government’s attempt to present radioisotopes as marvelous dividends of the atomic age was undercut in the 1950s by the fallout debates, as scientists and citizens recognized the hazards of low-level radiation. Creager reveals that growing consciousness of the danger of radioactivity did not reduce the demand for radioisotopes at hospitals and laboratories, but it did change their popular representation from a therapeutic agent to an environmental poison. She then demonstrates how, by the late twentieth century, public fear of radioactivity overshadowed any appreciation of the positive consequences of the AEC’s provision of radioisotopes for research and medicine.

Understanding Metaphors in the Life Sciences

Understanding Metaphors in the Life Sciences PDF

Author: Andrew S. Reynolds

Publisher: Cambridge University Press

Published: 2022-04-28

Total Pages: 223

ISBN-13: 1108945015

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Covering a range of metaphors from a diverse field of sciences, from cell and molecular biology to evolution, ecology, and biomedicine, Understanding Metaphors in the Life Sciences explores the positive and negative implications of the widespread use of metaphors in the biological and life sciences. From genetic codes, programs, and blueprints, to cell factories, survival of the fittest, the tree of life, selfish genes, and ecological niches, to genome editing with CRISPR's molecular scissors, metaphors are ubiquitous and vital components of the modern life sciences. But how exactly do metaphors help scientists to understand the objects they study? How can they mislead both scientists and laypeople alike? And what should we all understand about the implications of science's reliance on metaphorical speech and thought for objective knowledge and adequate public policy informed by science? This book will literally help you to better understand the metaphorical dimensions of science.

Model Based Inference in the Life Sciences

Model Based Inference in the Life Sciences PDF

Author: David R. Anderson

Publisher: Springer Science & Business Media

Published: 2007-12-22

Total Pages: 203

ISBN-13: 0387740759

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This textbook introduces a science philosophy called "information theoretic" based on Kullback-Leibler information theory. It focuses on a science philosophy based on "multiple working hypotheses" and statistical models to represent them. The text is written for people new to the information-theoretic approaches to statistical inference, whether graduate students, post-docs, or professionals. Readers are however expected to have a background in general statistical principles, regression analysis, and some exposure to likelihood methods. This is not an elementary text as it assumes reasonable competence in modeling and parameter estimation.