A Cultural History of Heredity

A Cultural History of Heredity PDF

Author: Staffan Müller-Wille

Publisher: University of Chicago Press

Published: 2012-06-22

Total Pages: 339

ISBN-13: 0226545725

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“Thought-provoking…any scientist interested in genetics will find this an enlightening look at the history of this field.”—Quarterly Review of Biology It was only around 1800 that heredity began to enter debates among physicians, breeders, and naturalists. Soon thereafter, it evolved into one of the most fundamental concepts of biology. Here, Staffan Muller-Wille and Hans-Jorg Rheinberger offer a succinct cultural history of the scientific concept of heredity. They outline the dramatic changes the idea has undergone since the early modern period and describe the political and technological developments that brought about these changes. They begin with an account of premodern theories of generation, showing that these were concerned with the procreation of individuals rather than with hereditary transmission, and reveal that when hereditarian thinking first emerged, it did so in a variety of cultural domains, such as politics and law, medicine, natural history, breeding, and anthropology. The authors then track theories of heredity from the late nineteenth century—when leading biologists considered it in light of growing societal concerns with race and eugenics—through the rise of classical and molecular genetics in the twentieth century, to today, as researchers apply sophisticated information technologies to understand heredity. What we come to see from this exquisite history is why it took such a long time for heredity to become a prominent concept in the life sciences, and why it gained such overwhelming importance in those sciences and the broader culture over the last two centuries.

Heredity Produced

Heredity Produced PDF

Author: Staffan Müller-Wille

Publisher: MIT Press

Published: 2007

Total Pages: 511

ISBN-13: 0262134764

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The cultural history of heredity: scholars from a range of disciplines discuss the evolution of the concept of heredity, from the Early Modern understanding of the act of "generation" to its later nineteenth-century definition as the transmission of characteristics across generations. Until the middle of the eighteenth century, the biological makeup of an organism was ascribed to an individual instance of "generation"--involving conception, pregnancy, embryonic development, parturition, lactation, and even astral influences and maternal mood--rather than the biological transmission of traits and characteristics. Discussions of heredity and inheritance took place largely in the legal and political sphere. In Heredity Produced, scholars from a broad range of disciplines explore the development of the concept of heredity from the early modern period to the era of Darwin and Mendel. The contributors examine the evolution of the concept in disparate cultural realms--including law, medicine, and natural history--and show that it did not coalesce into a more general understanding of heredity until the mid-nineteenth century. They consider inheritance and kinship in a legal context; the classification of certain diseases as hereditary; the study of botany; animal and plant breeding and hybridization for desirable characteristics; theories of generation and evolution; and anthropology and its study of physical differences among humans, particularly skin color. The editors argue that only when people, animals, and plants became more mobile--and were separated from their natural habitats through exploration, colonialism, and other causes--could scientists distinguish between inherited and environmentally induced traits and develop a coherent theory of heredity. Contributors David Sabean, Silvia De Renzi, Ulrike Vedder, Carlos López Beltrán, Phillip K. Wilson, Laure Cartron, Staffan Müller-Wille, Marc J. Ratcliff, Roger Wood, Mary Terrall, Peter McLaughlin, François Duchesneau, Ohad Parnes, Renato Mazzolini, Paul White, Nicolas Pethes, Stefan Willer, Helmuth Müller-Sievers

Who Wrote the Book of Life?

Who Wrote the Book of Life? PDF

Author: Lily E. Kay

Publisher: Stanford University Press

Published: 2000

Total Pages: 476

ISBN-13: 9780804734172

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This is a detailed history of one of the most important and dramatic episodes in modern science, recounted from the novel vantage point of the dawn of the information age and its impact on representations of nature, heredity, and society. Drawing on archives, published sources, and interviews, the author situates work on the genetic code (1953-70) within the history of life science, the rise of communication technosciences (cybernetics, information theory, and computers), the intersection of molecular biology with cryptanalysis and linguistics, and the social history of postwar Europe and the United States. Kay draws out the historical specificity in the process by which the central biological problem of DNA-based protein synthesis came to be metaphorically represented as an information code and a writing technology—and consequently as a “book of life.” This molecular writing and reading is part of the cultural production of the Nuclear Age, its power amplified by the centuries-old theistic resonance of the “book of life” metaphor. Yet, as the author points out, these are just metaphors: analogies, not ontologies. Necessary and productive as they have been, they have their epistemological limitations. Deploying analyses of language, cryptology, and information theory, the author persuasively argues that, technically speaking, the genetic code is not a code, DNA is not a language, and the genome is not an information system (objections voiced by experts as early as the 1950s). Thus her historical reconstruction and analyses also serve as a critique of the new genomic biopower. Genomic textuality has become a fact of life, a metaphor literalized, she claims, as human genome projects promise new levels of control over life through the meta-level of information: control of the word (the DNA sequences) and its editing and rewriting. But the author shows how the humbling limits of these scriptural metaphors also pose a challenge to the textual and material mastery of the genomic “book of life.”

Heredity Explored

Heredity Explored PDF

Author: Staffan Muller-Wille

Publisher: MIT Press

Published: 2016-07-29

Total Pages: 480

ISBN-13: 0262332280

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Investigations of how the understanding of heredity developed in scientific, medical, agro-industrial, and political contexts of the late nineteenth and early twentieth centuries. This book examines the wide range of scientific and social arenas in which the concept of inheritance gained relevance in the late nineteenth and early twentieth centuries. Although genetics emerged as a scientific discipline during this period, the idea of inheritance also played a role in a variety of medical, agricultural, industrial, and political contexts. The book, which follows an earlier collection, Heredity Produced (covering the period 1500 to 1870), addresses heredity in national debates over identity, kinship, and reproduction; biopolitical conceptions of heredity, degeneration, and gender; agro-industrial contexts for newly emerging genetic rationality; heredity and medical research; and the genealogical constructs and experimental systems of genetics that turned heredity into a representable and manipulable object. Taken together, the essays in Heredity Explored show that a history of heredity includes much more than the history of genetics, and that knowledge of heredity was always more than the knowledge formulated as Mendelism. It was the broader public discourse of heredity in all its contexts that made modern genetics possible. Contributors Caroline Arni, Christophe Bonneuil, Christina Brandt, Luis Campos, Jean-Paul Gaudillière, Bernd Gausemeier, Jean Gayon, Veronika Lipphardt, Ilana Löwy, J. Andrew Mendelsohn, Staffan Müller-Wille, Diane B. Paul, Theodore M. Porter, Alain Pottage, Hans-Jörg Rheinberger, Marsha L. Richmond, Helga Satzinger, Judy Johns Schloegel, Alexander von Schwerin, Hamish G. Spencer, Ulrike Vedder

Extended Heredity

Extended Heredity PDF

Author: Russell Bonduriansky

Publisher: Princeton University Press

Published: 2020-04-14

Total Pages: 304

ISBN-13: 0691204144

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Bonduriansky and Day challenge the premise that genes alone mediate the transmission of biological information across generations and provide the raw material for natural selection. They explore the latest research showing that what happens during our lifetimes—and even our parents’ and grandparents’ lifetimes—can influence the features of our descendants. Based on this evidence, Bonduriansky and Day develop an extended concept of heredity that upends ideas about how traits can and cannot be transmitted across generations, opening the door to a new understanding of inheritance, evolution, and even human health. --Adapted from publisher description.

The Emergence of Genetic Rationality

The Emergence of Genetic Rationality PDF

Author: Phillip Thurtle

Publisher: University of Washington Press

Published: 2007

Total Pages: 396

ISBN-13: 0295987502

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Both the science of genetics and the practice of breeding plants or animals required extensive record keeping. The author claims that modern science was born when organizational systems (e.g., vertical files, standardized forms, and middle managers) were developed to manage and make sense of massive amounts of information. He argues that the introduction of such information processing forms, along with the cultural incentives for implementing them, sparked new ways of exploring how living forms were related to each other.

The Invisible History of the Human Race

The Invisible History of the Human Race PDF

Author: Christine Kenneally

Publisher: ReadHowYouWant.com

Published: 2015-01-29

Total Pages: 477

ISBN-13: 1458798704

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A New York Times Notable Book of 2014 We are doomed to repeat history if we fail to learn from it, but how are we affected by the forces that are invisible to us? What role does Neanderthal DNA play in our genetic makeup? How did the theory of eugenics embraced by Nazi Germany first develop? How is trust passed down in Africa, and silence inherited in Tasmania? How are private companies like Ancestry.com uncovering, preserving and potentially editing the past? In The Invisible History of the Human Race, Christine Kenneally reveals that, remarkably, it is not only our biological history that is coded in our DNA, but also our social history. She breaks down myths of determinism and draws on cutting - edge research to explore how both historical artefacts and our DNA tell us where we have come from and where we may be going.

Heredity under the Microscope

Heredity under the Microscope PDF

Author: Soraya de Chadarevian

Publisher: University of Chicago Press

Published: 2020-07-02

Total Pages: 318

ISBN-13: 022668511X

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By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms. Telling this history in full for the first time, Soraya de Chadarevian argues that the often bewildering variety of observations made under the microscope were central to the study of human genetics. Making space for microscope-based practices alongside molecular approaches, de Chadarevian analyzes the close connections between genetics and an array of scientific, medical, ethical, legal, and policy concerns in the atomic age. By exploring the visual evidence provided by chromosome research in the context of postwar biology and medicine, Heredity under the Microscope sheds new light on the cultural history of the human genome.

A Cultural History of Heredity

A Cultural History of Heredity PDF

Author: Staffan Müller-Wille

Publisher: University of Chicago Press

Published: 2012-06-26

Total Pages: 339

ISBN-13: 0226545709

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Heredity: knowledge and power -- Generation, reproduction, evolution -- Heredity in separate domains -- First syntheses -- Heredity, race, and eugenics -- Disciplining heredity -- Heredity and molecular biology -- Gene technology, genomics, postgenomics: attempt at an outlook.